Effect of Dietary Sodium and Potassium Citrate on Renal Mineral Handling

Not Applicable

• Conditions: Kidney Stone
• Interventions: Dietary Supplement: Sodium and Potassium Citrate; Dietary Supplement: Placebo

• Registration Number: NCT03281928
• Lead Sponsor: University of Chicago

Brief Summary

This study intends to characterize the affect of sodium and potassium citrate in the diet on renal function.

Detailed Description

Not available

Basic Information
|
Recruitment & Eligibility
|
Study & Design
|
Trial Locations

Study Timeline

• Study First Submitted: 2017-09-08
• Study First Submitted QC: 2017-09-08
• Study First Posted: 2017-09-13
• Study Start: 2017-10-01
• Status Verified: 2021-10
• Last Update Submitted: 2021-10-08
• Last Update Posted: 2021-10-11
• Primary Completion: 2022-12-20
• Study Completion: 2022-12-20

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 52

Inclusion Criteria

• age 18 - 70, approximately equal numbers of men and women
• studied by endoscopy with complete papillary mapping and grading
• stone formers

Read More

Exclusion Criteria

• Patients with primary renal diseases or renal impairment (eGFR < 90), or medical conditions such as diabetes, or systemic diseases or medications that alter calcium metabolism
• Patients with known bladder voiding problems

Read More

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
High Sodium plus Potassium Citrate	Sodium and Potassium Citrate	-
Low Sodium plus Potassium Citrate	Sodium and Potassium Citrate	-
Low Sodium plus placebo	Placebo	-
High Sodium plus placebo	Placebo	-

Primary Outcome Measures

Name	Time	Method
Urine Calcium levels	10 days	Amount of calcium in the urine will be measured

Trial Locations

Locations (1)

University of Chicago Medical Center; 🇺🇸 Chicago, Illinois, United States