Effect of Dietary Sodium and Potassium Citrate on Renal Mineral Handling
Not Applicable
Terminated
- Conditions
- Kidney Stone
- Registration Number
- NCT03281928
- Lead Sponsor
- University of Chicago
- Brief Summary
This study intends to characterize the affect of sodium and potassium citrate in the diet on renal function.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- TERMINATED
- Sex
- All
- Target Recruitment
- 30
Inclusion Criteria
- age 18 - 70, approximately equal numbers of men and women
- studied by endoscopy with complete papillary mapping and grading
- stone formers
Exclusion Criteria
- Patients with primary renal diseases or renal impairment (eGFR < 90), or medical conditions such as diabetes, or systemic diseases or medications that alter calcium metabolism
- Patients with known bladder voiding problems
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- CROSSOVER
- Primary Outcome Measures
Name Time Method Urine Calcium levels 10 days Amount of calcium in the urine will be measured
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms explain sodium and potassium citrate's impact on renal mineral handling in kidney stone patients?
How does dietary sodium and potassium citrate compare to standard-of-care treatments for kidney stone prevention in terms of efficacy and safety?
Are there specific biomarkers that can predict individual patient response to potassium citrate therapy in nephrolithiasis?
What are the potential adverse events associated with long-term use of potassium citrate in renal stone management and how can they be mitigated?
What combination therapies involving potassium citrate are being explored for improving renal function and reducing kidney stone recurrence?
Trial Locations
- Locations (1)
University of Chicago Medical Center
🇺🇸Chicago, Illinois, United States
University of Chicago Medical Center🇺🇸Chicago, Illinois, United States