Structural Imaging Assisted Retinal Fluorescence Lifetime Imager (STARFLI)
- Conditions
- Retinal Disease
- Registration Number
- NCT05819307
- Lead Sponsor
- Insel Gruppe AG, University Hospital Bern
- Brief Summary
To investigate the feasibility of a combined OCT/FLIM device
- Detailed Description
To investigate the feasibility of a combined Optical coherence tomography/ Fluorescence Lifetime Measurement (OCT/FLIM) device.
Recruitment & Eligibility
- Status
- NOT_YET_RECRUITING
- Sex
- All
- Target Recruitment
- 70
- Subject must be willing to give written informed consent
- Age: Patients and Probands 18 years or greater
- Both eyes will be assessed in the study
- Patients not willing or able to sign informed consent
- Patients younger than 18 years
- Patients with epilepsy
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Feasibility of device 1 year We will organize and perform an observational study with the prototype OCT+FLIM device and contribute the acquired OCT/FLIM datasets from eyes of different age and status of the crystalline lens.
- Secondary Outcome Measures
Name Time Method To provide two key technology aspects of the project: 1 year A. The first will be to bring forward a novel registration strategy for calibrated OCT and FLIM modalities, so that these can be used in conjunction.
B. The second will be to develop an image calibration and normalization method using the measured lens fluorescence lifetime and possibly also structural (OCT) information on lens and retina, so that data acquired by the device can be used across different patients in a consistent way.
Trial Locations
- Locations (1)
Department of Ophthalmology, Bern University Hospital, Bern, 3010 Bern, Switzerland
🇨ðŸ‡Bern, Switzerland