Focussen bij mensen met de gedragsvariant van frontotemporale dementie

• Conditions: Disinhibited behavior in the behavioral variant of frontotemporal dementia

• Registration Number: NL-OMON27059
• Lead Sponsor: Radboud University Medical Center (RadboudUMC), Nijmegen

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 28 February 2024

Recruitment & Eligibility

• Status: Other
• Sex: Not specified
• Target Recruitment: 6

Inclusion Criteria

Residents of young-onset dementia special care units (YOD SCU’s); a) diagnosed with the behavioral variant of frontotemporal dementia, b) who show disinhibited behavior and c) have been admitted at the YOD SCU for at least 6 weeks

Exclusion Criteria

- Lack of informed consent
- Advanced dementia

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
•Specific disinhibited behavior, scored on a list developed for the specific disinhibited behavior of a resident by an observer<br>•Well-being, scored on a adjusted version of the EQ-5D thermometer<br>•Intervention moments by health care professionals, established in advance to the multiple case study during a visitation meeting, behavioral visit or multidisciplinary consultation and scored by an observer<br>•Current use of psychotropic drugs (in advance to and at the end of the multiple case study), identified by a (retrospective) view of the electronic prescription systems

Secondary Outcome Measures

Name	Time	Method
Descriptive measures:<br>•Relevant medical history (prior to and during admission) with specific attention for the disinhibited behavior. This will be identified using patient records. Eventually, health care professionals and/or family members will be consulted.<br>•Dementia severity with the Global Detoriation Scale (GDS)<br>•Cognitive functions with the Mini Mental State Examination (MMSE), Severe Impairment Battery Short Version (SIB-S) and Frontal Assessment Battery (FAB)<br>•Neuropsychiatric symptoms with the Neuropsychiatric Inventory Nursing Home Version (NPI-NH)<br>•Disinhibition and related behaviors with the Frontal Behavioral Inventory (FBI) and Middelheim Frontality Score (MFS)