Modifications of the Growth Hormone/IGF1 Axis in Heart Failure Patients

Assistance Publique - Hôpitaux de Paris0 个研究点目标入组 180 人开始时间: 2000年9月最近更新: 2005年9月19日

适应症

试验速览

阶段: 不适用
状态: 终止
发起方: Assistance Publique - Hôpitaux de Paris
入组人数: 180

研究概览研究设计入排标准研究者记录与标识符相似试验

研究概览

简要总结

Heart failure induces modification in several neurohormonal systems. The aim of this study is to determine if the growth hormone/IGF1 axis is modified in heart failure patients compared to healthy volunteers.

详细描述

One hundred and sixty three heart failure patients were evaluated by clinical examination, echocardiography, exercise test and measurement of blood BNP. Growth hormone and IGF-1 plasma levels were determined in each patient. The same biological measurements were performed in a group of 148 healthy controls. Comparisons were performed between groups for Growth hormone plasma level, IGF-1 plasma level and Growth hormone/IGF-1 index. A correlation between the severity of heart failure and the different biological parameters was searched.

研究设计

研究类型: Observational
观察模型: Case Control
时间视角: Other

入排标准

年龄范围: 18 Years 至 —（Adult, Older Adult）
性别: All
接受健康志愿者: 否

入选标准

•Heart failure patients in stable condition

排除标准

•pituitary disease

研究者

发起方

Assistance Publique - Hôpitaux de Paris

申办方类型

Other

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