Effect of lajjalu kera in fissure-in-ano
Trial Snapshot
- Phase
- Not Applicable
- Status
- Not yet recruiting
- Sponsor
- Enrollment
- 30
- Locations
- 1
- Primary Endpoint
- Pain,
Study Overview
Brief Summary
Fissure-in-ano is a painful anorectal condition commonly causing bleeding per rectum and affecting a large portion of the population. It can be acute, with recent tears and sphincter spasm, or chronic, with inflamed and scarred margins. While acute cases may heal with conservative measures like sitz baths and topical agents, chronic fissures often require surgical treatment, which may lead to complications such as bleeding or incontinence. In Ayurveda, the condition is correlated with Parikartika, described with symptoms like cutting pain, burning sensation, and difficulty in defecation. Classical treatments include Pichabasti, Anuvasana Basti, and application of medicated oils to pacify Vata and Pitta. This study evaluates the effect of Lajjalu Kera Taila—a formulation using Lajjalu (Mimosa pudica), known for its wound-healing and hemostatic properties, and Kera Taila (coconut oil), which is anti-inflammatory and lubricating. anal instillation of lajjalu kera done for 14 days in 30 patients aged 18–65 years with fissure-in-ano at Government Ayurveda College, Pariyaram. The results showed significant reduction in symptoms, suggesting that this Ayurvedic approach is a safe, effective, and economical alternative to conventional surgical management.
Study Design
- Study Type
- Interventional
- Allocation
- Na
- Masking
- None
Eligibility Criteria
- Ages
- 18.00 Year(s) to 65.00 Year(s) (—)
- Sex
- All
Inclusion Criteria
- •The diagnosis will be confirmed by a Linear ulcer at the long axis of anal canal either at the posterior or anterior midline along with any of the two mentioned below Pain during and after defecation in the anal region Burning sensation after defecation Blood streaks on the stool Age group between 18 to 65 years.
Exclusion Criteria
- •Participants with known case of Ca rectum Ca anus Participants with fistula in ano Known case of fissure secondary to tuberculosis Inflammatory bowel disease syphilis and other systemic disease pertaining to Colo-rectum will be excluded from the study Patients with diseases like HIV & Hepatitis B Bleeding disorders Patients with uncontrolled DM.
Outcomes
Primary Outcomes
Pain,
Time Frame: assessment on 0th 8th 15th day | assessment on 30th day
Bleeding
Time Frame: assessment on 0th 8th 15th day | assessment on 30th day
Burning sensation
Time Frame: assessment on 0th 8th 15th day | assessment on 30th day
Sphincter spasm
Time Frame: assessment on 0th 8th 15th day | assessment on 30th day
length of ulcer
Time Frame: assessment on 0th 8th 15th day | assessment on 30th day
Secondary Outcomes
No secondary outcomes reported
Investigators
Vyshnavi M S
Government ayurveda medical college pariyaram kannur
