Prospective observational study for advanced lung cancer with interstitial lung disease
Not Applicable
- Conditions
- Advanced lung cancer with interstitial lung disease
- Registration Number
- JPRN-UMIN000019370
- Lead Sponsor
- Hamamatsu University School of Medicine
- Brief Summary
Among 124 patients enrolled, 109 patients who received chemotherapy were analyzed. After registration, 23 patients developed AE-ILD. The logistic analysis revealed that lower %FVC significantly increased the risk of AE-ILD. Overall response rates/median overall survival times in non-small-cell lung cancer and small-cell lung cancer for the first-line chemotherapy were 41%/8.9??onths and 91%/12.2??onths, respectively.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 124
Inclusion Criteria
Not provided
Exclusion Criteria
1. Post-radiation fibrosis alone
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Safety, particulary for the frequency and severity of chemotherapy-induced acute exacerbation of interstitial lung disease
- Secondary Outcome Measures
Name Time Method Efficacy including response rate and progression-free survival