Contralateral Strength-training After Anterior Cruciate Ligament (ACL) Reconstruction

Not Applicable

Completed

• Conditions: Muscle Weakness After Anterior Cruciate Ligament Reconstruction
• Interventions: Behavioral: Neuromuscular electrical stimulation; Behavioral: eccentric training

• Registration Number: NCT01901965
• Lead Sponsor: Schulthess Klinik

Brief Summary

The main aims of the study are (1) to examine the impact of contralateral strength training on the quadriceps muscle function after ACL surgery and (2) to compare the magnitude of cross-education induced by NMES versus eccentric strength training.

Detailed Description

Not available

Study Timeline

• Study Start: 2013-05
• Study First Submitted: 2013-05-29
• Study First Submitted QC: 2013-07-15
• Study First Posted: 2013-07-17
• Primary Completion: 2016-10
• Study Completion: 2016-11
• Status Verified: 2023-12
• Last Update Submitted: 2023-12-18
• Last Update Posted: 2023-12-19

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 36

Inclusion Criteria

• patients scheduled for ACL reconstruction surgery

Exclusion Criteria

• Concomitant lower limb injury or disorder
• previous lower extremity open surgery on the contralateral lower limb
• cardiac disease
• pregnancy

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
NMES	Neuromuscular electrical stimulation	neuromuscular electrical stimulation (NMES) of the quadriceps muscle with Kneehab
eccentric training	eccentric training	unilateral eccentric resistance exercises
sham NMES	Neuromuscular electrical stimulation	neuromuscular electrical stimulation of the quadriceps muscle with intensity which causes no visible contraction or displacement of the leg (activation below motor threshold)

Primary Outcome Measures

Name	Time	Method
Change in bilateral quadriceps muscle strength [Nm]	1-2weeks preoperative/ 2weeks/ 8weeks/ 6month
Change in quadriceps muscle activation	1-2 weeks preoperative/ 2weeks/ 8weeks/ 6month

Secondary Outcome Measures

Name	Time	Method
functional test outcomes	6month postop	Assessment of present functional status by means of hop tests
Change in self-reported questionnaire outcomes (KOOS, WOMAClk)	1-2weeks preoperative/ 2weeks/ 8weeks/ 6 month
Change in muscle architecture	1-2 weeks preoperative/ 2weeks/ 8weeks/ 6month

Trial Locations

Locations (1)

Neuromuscular Research Laboratory, Schulthess Klinik; 🇨🇭 Zurich, ZH, Switzerland