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Clinical Trials/NCT00466570
NCT00466570WithdrawnNot Applicable

Prospective Randomized Comparison of Zymar(Gatifloxacin) and Vigamox (Moxifloxacin) in Killing Conjunctival Bacterial Flora Following a One-hour

Stanford University0 sitesStarted: April 1, 2007Last updated:
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Conditions
Drugs

Trial Snapshot

Phase
Not Applicable
Status
Withdrawn
Primary Endpoint
Antibiotic killing of conjunctival bacterial flora 1 hour after application
Study OverviewStudy DesignEligibility CriteriaOutcomesInvestigatorsRecords & IdentifiersSimilar Trials

Study Overview

Brief Summary

Topical ophthalmic antibiotics are common prescribed just prior to eye surgery to lower the risk of infection. Previous studies have suggested that antibiotics containing a preservative (Zymar) kill bacteria much quicker than those without a preservative (Vigamox). The purpose of this research is to compare how quickly to the two commonly prescribed antibiotics eliminate bacteria from the eye surface.

Study Design

Study Type
Interventional
Allocation
Randomized
Intervention Model
Factorial
Primary Purpose
Prevention
Masking
Single

Eligibility Criteria

Ages
50 Years to — (Adult, Older Adult)
Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • •Age- older than 50 years of age
  • •Diagnosis- Cataract or had cataract surgery

Exclusion Criteria

  • •Systemic or topical antibiotic treatment within 30 days
  • •Use of systemic or topical steroids
  • •Active ocular infection
  • •Ocular surgery in the past 6 months
  • •Allergy to fluoroquinolones

Outcomes

Primary Outcomes

Antibiotic killing of conjunctival bacterial flora 1 hour after application

Secondary Outcomes

No secondary outcomes reported

Investigators

Sponsor Class
Other
Responsible Party
Principal Investigator
Principal Investigator

Christopher Ta

Principal Investigator

Stanford University

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