The Impact of Right Ventricular Pacing on Tricuspid Regurgitation
试验速览
- 阶段
- 不适用
- 入组人数
- 50
- 试验地点
- 1
研究概览
简要总结
"1" To examine whether right ventricular pacing has an impact on tricuspid regurgitation grade that is related to pacing rather than to valve closure interference by the electrode.
详细描述
"1" Traditionally, tricuspid regurgitation in the presence of pacemaker is attributed to the physical interference of the valve closure by the electrode.
"2" Right ventricular pacing may be associated with dyssynchrony in contraction of the right ventricular wall (i.e. septum and free wall.
"3" The tricuspid sub-valvar apparatus is anchored to the septum and free wall, thus may be sensitive to dyssynchrony in those wals contraction.
"4" The study hypothesis is that the dyssynchrony in right ventricular contraction, induced by pacing, may increase tricuspid regurgitation grade and that this is a mechanism is independent of the mechanical effect of the electrode on the valve closure.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age >18 years
- •Permanent pacemaker
排除标准
- •Epicardial pacing
- •Left ventricular dysfunction
- •Organic tricuspid regurgitation
- •Bi-ventricular pacemaker
- •Atrial fibrillation
- •Complete pacemaker dependence