The Impact of Right Ventricular Pacing on Tricuspid Regurgitation
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Tricuspid Regurgitation
- Sponsor
- Rabin Medical Center
- Enrollment
- 50
- Locations
- 1
- Last Updated
- 17 years ago
Overview
Brief Summary
"1" To examine whether right ventricular pacing has an impact on tricuspid regurgitation grade that is related to pacing rather than to valve closure interference by the electrode.
Detailed Description
"1" Traditionally, tricuspid regurgitation in the presence of pacemaker is attributed to the physical interference of the valve closure by the electrode. "2" Right ventricular pacing may be associated with dyssynchrony in contraction of the right ventricular wall (i.e. septum and free wall. "3" The tricuspid sub-valvar apparatus is anchored to the septum and free wall, thus may be sensitive to dyssynchrony in those wals contraction. "4" The study hypothesis is that the dyssynchrony in right ventricular contraction, induced by pacing, may increase tricuspid regurgitation grade and that this is a mechanism is independent of the mechanical effect of the electrode on the valve closure.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Age \>18 years
- •Permanent pacemaker
Exclusion Criteria
- •Epicardial pacing
- •Left ventricular dysfunction
- •Organic tricuspid regurgitation
- •Bi-ventricular pacemaker
- •Atrial fibrillation
- •Complete pacemaker dependence
Outcomes
Primary Outcomes
Not specified