The Mechanism of Non-invasive Brain Stimulation for Therapy of Chronic Auditory Verbal Hallucinations in Schizophrenia

Charite University, Berlin, Germany1 site in 1 country30 target enrollmentMarch 2013

ConditionsAuditory Verbal Hallucinations Schizophrenia

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Auditory Verbal Hallucinations
Sponsor: Charite University, Berlin, Germany
Enrollment: 30
Locations: 1
Primary Endpoint: Change of Auditory Hallucination Rating Scale score
Status: Completed
Last Updated: 9 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

The current study investigates the basic principles that underlie the efficacy of transcranial direct current stimulation for chronic auditory verbal hallucinations in schizophrenia in a multimodal design.

Registry

clinicaltrials.gov

Start Date

March 2013

End Date

December 2015

Last Updated

9 years ago

Study Type

Interventional

Study Design

Parallel

Sex

All

Investigators

Sponsor

Charite University, Berlin, Germany

Responsible Party

Principal Investigator

Andres Neuhaus, MD

M.D.

Charite University, Berlin, Germany

Eligibility Criteria

Inclusion Criteria

•diagnosis of schizophrenia
•chronic auditory verbal hallucinations
•right-handed

Exclusion Criteria

•drug abuse other than nicotine
•severe cognitive deficits
•severe medical conditions
•severe neurological disorders
•severe microangiopathy
•history of electroconvulsive therapy
•pregnancy or lactation

Outcomes

Primary Outcomes

Change of Auditory Hallucination Rating Scale score

Time Frame: baseline; 3 days after intervention; 3 months after intervention

Auditory Hallucination Rating Scale score will be assessed at baseline; changes thereof at 3 days after intervention and 3 months after intervention are primary outcome measures