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Efficacy and safety of tenofovir disoproxil fumarete (TDF) in nucleos(t)ide analogue-naive patients with hepatitis B virus

Not Applicable
Recruiting
Conditions
Patients with chronic hepatitis B virus infection
Registration Number
JPRN-UMIN000017728
Lead Sponsor
Osaka University Graduate School of Medicine, Department of Gastroenterology and Hepatology
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
200
Inclusion Criteria

Not provided

Exclusion Criteria

1) pregnant woman 2) co-infection with other hepatitis virus (HCV/HDV/HIV) 3) contraindication to tenofovir disoploxil fumarate

Study & Design

Study Type
Observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
probability of HBV DNA negativity dicrease rate of HB surface antigen level dicrease rate of HB core-related antigen probability of HBe antigen seroconversion probability of ALT normalization cumulative incidence rate of hepatocellular carcinoma
Secondary Outcome Measures
NameTimeMethod
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