Comparison of analgesic efficacy of ultrasound guided quadratus lumborum block versus transversus abdominis plane block for pyeloplasty for children- a randomized, double blind, controlled trial.
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- Secondary Objectives
研究概览
简要总结
Renal surgeries are commonly performed procedures in children and are associated with significant post-operative pain.Effective postoperative analgesia is essential to allow coughing, early mobilization, and to reduce the incidence of post-operative respiratory complications. Compared to systemic opioids , neuraxial analgesia and peripheral nerve blockade techniques can provide superior analgesia while avoiding majority of side effects of opioids as well as NSAIDs.
The transversus abdominis plane (TAP) block and quadratus lumborum(QL) block are the truncal nerve blocks that targets the lower thoracic and upper lumbar nerves as they course through the inter-fascial planes and provides analgesia for procedures involving the abdominal wall.
Quadratus lumborum (QL) block is a newly introduced variation of TAP block, reported to provide excellent post-operative analgesia in; pediatric patients undergoing radical nephrectomy (2), colostomy closure (3), pyeloplasty .
研究设计
- 研究类型
- Interventional
- 分配方式
- Computer generated randomization
- 盲法
- Participant and Outcome Assessor Blinded
入排标准
- 年龄范围
- 2.00 Year(s) 至 10.00 Year(s)（—）
- 性别
- All
入选标准
- •American Society of Anaesthesiology physical status I and II Posted for elective pyeloplasty.
排除标准
- •Refusal of parents or guardians to participate in the study
- •Developmental delay and mental retardation
- •History of sensitivity to drugs used in the study
- •Coagulopathy
- •Infection at the puncture site
- •Significant cardiac renal or liver disease.
结局指标
主要结局
Secondary Objectives
时间窗: at 1, 2, 4, 6, 8, 12, 18, 24 hours
To compare the intraoperative and post operative analgesic consumptions and post operative VAS scores
时间窗: at 1, 2, 4, 6, 8, 12, 18, 24 hours
Primary outcome
时间窗: at 1, 2, 4, 6, 8, 12, 18, 24 hours
To compare the incidence of nausea or vomiting, excessive sedation and respiratory depression
时间窗: at 1, 2, 4, 6, 8, 12, 18, 24 hours
次要结局
- Secondary Objectives(To compare the incidence of nausea or vomiting, excessive sedation and respiratory depression)