Coronary imaging with optical coherence tomography and computational modelling for the prediction of major adverse cardiovascular events in patients with high risk coronary artery disease.

Abbott Vascular0 个研究点目标入组 582 人开始时间: 2018年10月11日最近更新: 2018年11月12日

适应症

试验速览

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•1. Patients who present to hospital with (1a) NSTEMI and who proceed to inpatient angiography or (1b) STEMI and who proceed to non-emergency in-patient angiography (late presenters, reperfused without PCI; patients who return to the catheter laboratory for in-patient treatment of non-infarct related additional coronary stenosis following initial primary PCI) or (1c) stable or unstable angina.
•2. One or more functionally significant coronary lesion where PCI is deemed appropriate
•3. Age 18 to 85 years old
•4. At least 2 major epicardial coronary arteries (left anterior descending, left circumflex, right coronary arteries) suitable for per protocol OCT.

•1. eGFR less than 40ml/min
•2. Unlikely to survive for at least 3 years due to comorbidity
•3. Coronary anatomy unsuitable for OCT
•4. Pregnancy
•5. Prior Coronary Artery Bypass Graft (CABG)
•6. At the time of acute presentation with STEMI treated with primary PCI (see inclusion criteria 1b)
•7. Refractory heart failure
•8. Known significant non-compliance with medication

发起方