ShorT and OPtimal duration of Dual AntiPlatelet Therapy-2 study - STOPDAPT-2

Ono Koh0 个研究点目标入组 3,045 人开始时间: 2019年3月26日最近更新: 2024年4月1日

适应症

试验速览

阶段: 4 期
状态: 已完成
发起方
入组人数: 3,045

研究概览入排标准研究者记录与标识符相似试验

研究概览

简要总结

For the patients receiving coronary stenting with DES, clopidogrel monotherapy following 1-month DAPT, compared with conventional aspirin monotherapy following 12-month DAPT, significantly reduced cardiovascular events at 5 years and was non-inferior in the primary endpoint, making it a promising new alternative to conventional therapy.

研究设计

研究类型: Interventional

入排标准

年龄范围: ot applicable 至 ot applicable（—）
性别: All

入选标准

•1) Patients who have undergone PCI with the everolimus-eluting cobalt-chromium stent (CoCr-EES, XienceTM) and have not experienced major complications (death, MI, stroke, or major bleeding) during hospital stay for treatment
•2) Patients who are capable of oral dual antiplatelet therapy consisting of aspirin and a P2Y12 receptor antagonist

排除标准

•1) Patients requiring oral anticoagulants
•2) Patients with medical history of intracranial hemorrhage
•3) Patients who have experienced serious complications (MI, stroke, and major bleeding) during hospital stay post-PCI
•4) Patients with DES other than Xience implanted in PCI performed at the time of enrollment.
•5) Patients with coronary bioabsorbable vascular scaffolds (BVS) implanted prior to or at the time of enrollment (including implantation cases in clinical trial)
•6) Patients confirmed to have no tolerability to clopidogrel before enrollment
•7) Patients requiring continuous administration of antiplatelet drugs (PDE3 inhibitors, prostaglandin preparations, etc.) other than aspirin and P2Y12 receptor antagonists (prasugrel, clopidogrel, and ticlopidine) at the time of enrollment

研究者

发起方

Ono Koh

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