Clinical evaluation of glycemic response, insulinemic response and satiety of plant-based diabetic-friendly Indian traditional mixed meals in overweight/obese women in India

Diabetes mellitus is a major public health problem worldwide affecting millions of people which is essentially due to dramatic changes in diet and lifestyle. It is a chronic disorder occurring due to elevated blood glucose levels and the inability of a body’s response to high blood glucose, which is caused by defects in insulin secretion and action. One of the major aims of chronic disease therapy is to normalize the blood glucose profile, including the fasting and postprandial blood glucose concentrations. Many carbohydrate foods provoke variable glycemic responses. Assessment of glycemic response is one of the effective methods to compare between various meal types.  Low glycemic foods and diets have been shown to improve glycemic control in diabetics and in non-diabetic subjects. The purpose of this study is to evaluate the glycemic and response, insulinemic response and satiety of plant-based diabetic-friendly Indian traditional mixed meals in overweight/obese women. The impact of mixed meals on the post prandial blood glucose response will be determined using finger prick capillary method (Hemocue 201) at 0, 30, 60, 90, 120 minutes. Intravenous blood will be collected to measure the fasting and post-prandial insulin levels. Satiety of the meals will also be evaluated using SLIM scale. Glycemic and insulinemic responses of reformulated traditional meals with diabetic-friendly ingredients will be known from the study results. Better control of diabetes and other lifestyle disorders expected, when results are shared with the general public.