Correlates and Mehcanisms Underlying Very Late Stent Thrombosis After Implantation of New Generation DES in China
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Enrollment
- 8,476
- Locations
- 1
- Primary Endpoint
- Very Late Stent Thrombosis
Study Overview
Brief Summary
The investigators sought to identify and verify the potential correlates and mechanisms of Very Late Stent Thrombosis (VLST) after the implantation of new generation drug eluting steng in China from an analysis of multicenter registries.
Detailed Description
This study represents a patient-level pooled analysis of patients undergoing percutaneous coronary intervention with stent implantation for acute coronary syndrome. Multiple aspects including clinical, angiographic, procedural characteristics , intravascular imaging results and blood samples were collected at index PCI and the time of VLST or CAG during follow-up, in order to reveal the potential mechanisms or risk factors that contribute to the development of VLST.
Study Design
- Study Type
- Observational
- Observational Model
- Cohort
- Time Perspective
- Prospective
Eligibility Criteria
- Ages
- 18 Years to — (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Patients>18y,admitted for acute coronary syndrome,successfully underwent PCI with at least one stent, sign informed consent.
Exclusion Criteria
- •Expected lifetime was less than 1 year for any severe disease(such as tumor,severe respiratory failure et al). There is a surgical plan for important organs within 1 year after surgery and anti-platelet drugs should be discontinued. Refusing to sign informed consent.Died prior to discharge. Poor compliance, unable to participate in regular follow-up.
Outcomes
Primary Outcomes
Very Late Stent Thrombosis
Time Frame: Five years
very late stent thrombosis demonstrated by coronary angiography
Secondary Outcomes
No secondary outcomes reported