Efficacy of Single Level Versus Bilevel Serratus Anterior Plane Block With Dexmedetomidine During Breast Cancer Surgery
Trial Snapshot
- Phase
- Not Applicable
- Status
- Recruiting
- Sponsor
- Enrollment
- 172
- Locations
- 2
- Primary Endpoint
- First time to receive analgesia
Study Overview
Brief Summary
This study aims to compare single level serratus block versus bilevel serratus block with and without dexmedetomidine in cancer patients undergoing modified radical mastectomy for breast cancer regarding pain control and possible side effects.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Prevention
- Masking
- Triple (Participant, Investigator, Outcomes Assessor)
Eligibility Criteria
- Ages
- 18 Years to 65 Years (Adult, Older Adult)
- Sex
- Female
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •patients scheduled for modified radical mastectomy,
- •Age 18-65 years,
Exclusion Criteria
- •patient refusal,
- •coagulation defects,
- •abnormal kidney or liver functions,
- •local infection at site of injection.
Arms & Interventions
Single level serratus anterior plane block with dexmedetomidine
the allocated patients will receive single injection serratus anterior plane block at the level of third rib with local anesthetics and dexmedetomidine
Intervention: Single level serratus anterior plane block with dexmedetomidine (Procedure)
Bilevel serratus anterior plane block
the allocated patients will receive injection serratus anterior plane block at 2 levels, the level of third rib and the level of the fifth rib with local anesthetics only
Intervention: Bilevel serratus anterior plane block (Procedure)
Bilevel serratus anterior plane block with dexmedetomidine
the allocated patients will receive injection serratus anterior plane block at 2 levels, the level of third rib and the level of the fifth rib with local anesthetics and dexmedetomidine
Intervention: Bilevel serratus anterior plane block with dexmedetomidine (Procedure)
Single level serratus anterior plane block
the allocated patients will receive single injection serratus anterior plane block at the level of third rib with local anesthetics only
Intervention: Single level serratus anterior plane block (Procedure)
Outcomes
Primary Outcomes
First time to receive analgesia
Time Frame: First 24 hours postoperatively
first time to receive morphine analgesia in hours
Total analgesic requisite
Time Frame: First 24 hours postoperatively
total amount of morphine consumption in the first 24 hours postoperatively in mg
Secondary Outcomes
- Pain scores(First 24 hours postoperatively)
- Side effects(First 24 hours postoperatively)
- Perioperative heart rate values(First 24 hours)
- Mean arterial blood pressure(First 24 hours)
Investigators
Walaa Youssef Elsabeeny
Assistant professor of Anesthesia and Pain management
National Cancer Institute, Egypt