Prevention of Colorectal Cancer Through Multiomics Blood Testing
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 48,995
- 试验地点
- 148
- 主要终点
- Sensitivity for Colorectal Cancer
研究概览
简要总结
The PREEMPT CRC study is a prospective multi-center observational study to validate a blood-based test for the early detection of colorectal cancer by collecting blood samples from average-risk participants who will undergo a routine screening colonoscopy.
详细描述
Freenome is using a type of artificial intelligence, called machine learning, to identify patterns of cell-free biomarkers in blood to detect cancer early. The purpose of this prospective multi-center observational study is to validate a blood-based test for the detection of colorectal cancer by collecting blood samples from average-risk participants who will undergo a routine screening colonoscopy.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 45 Years 至 85 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- 未提供
排除标准
- 未提供
结局指标
主要结局
Sensitivity for Colorectal Cancer
时间窗: 90 days
Proportion of participants with a positive test result among those who had a diagnosis of colorectal cancer
Specificity for Advanced Colorectal Neoplasia
时间窗: 90 days
Proportion of participants with a negative test result among those who had non-advanced precancerous lesions or negative findings (non-neoplastic or no findings)
Negative Predictive Value for Advanced Colorectal Neoplasia
时间窗: 90 days
Proportion of participants with a diagnosis of non-advanced precancerous lesions or negative findings (non-neoplastic or no findings) among those who had a negative test result
Positive Predictive Value for Advanced Colorectal Neoplasia
时间窗: 90 days
Proportion of participants with a diagnosis of colorectal cancer or advanced precancerous lesions among those who had a positive test result
次要结局
- Sensitivity for Advanced Precancerous Lesion(90 days)