NCT01314820已完成不适用
Effects of Joint Effusion on Quadriceps Muscle in Patients With Knee Osteoarthritis
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 40
- 试验地点
- 2
- 主要终点
- the peak torque of the knee extensors
研究概览
简要总结
The present study investigated whether the presence of fluid in the joint affected peak torque and the root mean square (RMS) values of surface electromyography (EMG) in patients symptomatic for osteoarthritis (OA).
详细描述
Several studies have shown that knee effusion influenced quadriceps muscle activity and induced quadriceps arthrogenic muscle inhibition in normal volunteers. However, the effect of joint effusion on the quadriceps of patients with OA is controversial,and few patients with OA have been included in studies of joint effusion.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- Single (Investigator)
入排标准
- 年龄范围
- 50 Years 至 75 Years（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •50 years old or older with knee osteoarthritis
- •knee pain without joint effusion confirmed by ultrasonography
排除标准
- •the presence of knee joint effusion determined using US
- •a history of knee injury or surgery
- •a history of knee injection within 3 months
- •a history of inflammatory arthritis
- •taking anticoagulants
- •balance or gait disturbance
- •diabetes mellitus
结局指标
主要结局
the peak torque of the knee extensors
时间窗: within 5 minutes after intervention
to evaluate the effect of effusion on the peak torque of the knee extensors
次要结局
- the root mean square values of the vastus medialis and vastus lateralis muscles(within 5 minutes after intervention)
研究者
研究点 (2)
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