Radiomic Modeling in Differentiating Uncomplicated From Complicated Acute Appendicitis
Recruiting
- Conditions
- Acute Appendicitis
- Interventions
- Diagnostic Test: without
- Registration Number
- NCT05843630
- Lead Sponsor
- Kecheng Zhang
- Brief Summary
Non-operative management (NOM) with antibiotics may be a safe alternative to surgery for uncomplicated appendicitis, but preoperative differentiation between uncomplicated and complicated appendicitis is challenging. The study aimed to develop a clinical-radiomics nomogram to distinguish uncomplicated from complicated appendicitis.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 250
Inclusion Criteria
- Pathologically diagnosed as acute appendicitis after appendectomy between January 2021 and December 2022.
Exclusion Criteria
- age less than 18 years (no upper age limit);
- without CT examination within a week before surgery;
- difficult to outline the contours of the appendix due to inflammatory exudate;
- lack of clinical information.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description Validation cohort 2 without Model validation in an independent validation cohort 2 Validation cohort 1 without Model validation in an independent validation cohort 1 Training cohort without Model construction based on training cohort
- Primary Outcome Measures
Name Time Method Accuracy of clinical-radiomic model for differentiating complicated from uncomplicated appendicitis January 2021 to December 2022 ROC curve will be plotted and the area under ROC curve will be compared
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Chinese PLA General Hospital First Medical Center
🇨🇳Beijing, China