Comparison of Intracanal Medicaments in Incidence of Post-Operative Endodontic Pain

Phase 2/3

Not yet recruiting

Conditions: Chronic apical periodontitis, , (2) ICD-10 Condition: K044||Acute apical periodontitis of pulpal origin,

Registration Number: CTRI/2021/03/032269

Lead Sponsor: Dr Abhilasha Bhawalkar

Brief Summary: This will be a study on 50 patients showing mild to moderate pain symptoms who will undergo root canal treatment .After doing the access cavity preparation,complete instrumentation with OneCurve(Micromega) rotary file, intracanal medicaments like Calcium hydroxide and 2% Chlorhexidine mixture, Septilin,Chitosan,10%Metronidazole and no medicament(Normal Saline) as divided equally(n=5) will be used and patients will be asked for post-operative pain at 6,12,24,36,72 and one week time phrame. Final step of Root Canal will be done after 7 days.

Detailed Description: Not available

Recruitment & Eligibility

Status: Not Yet Recruiting

Sex: All

Target Recruitment: 50

Inclusion Criteria

1.Vital and non-vital Mandibular 1st and 2nd molars 2.Presence of occlusal caries 3.Symptomatic patients with moderate pain 4.Radiographically verified Apical Periodontitis with widening of the Periodontol Ligament Space 5.Periapical lesion less than 2mm 6.Fully formed root apices 7.Age 25-45 yrs 8.Systemically Healthy Patients.

Exclusion Criteria

1.Large periapical(>2mm) lesion seen radiographically 2.Roots with apical patency equal to or more than #25 3.Teeth with Proximal Caries 4.Pulpal involvements with any other tooth from that side 5.Roots showing internal and external resorption 6.Cracked roots 7.Calcified root 8.Root Curvatures >20o.
9.Developmental anomalies 10.Radix Entomolaris/Paramolaris 11.Severe attrition 12.Traumatized teeth 13.Opposing prosthesis 14.Teeth with sinus tract or abscess 15.Teeth with Periodontal Pockets 16.Patients having any systemic condition eg.Diabetes,Hypertension,Hyperthyroidism,Hypothyroidism etc,influencing the outcome of root canal treatment 17.
Patients on any oral medication or having consumed any medication(i.e.anti-inflammatory-analgesic,antibiotic) within 48 hrs of treatment.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Primary outcome is pain reduction	6,12,24,48,72 hrs, one week

Secondary Outcome Measures

Name	Time	Method
No occurance of pain and no need for systemic medication	6,12,24,48,72 hrs and one week

Trial Locations

Locations (1): Dr. D.Y.Patil Dental College and Hospital,Pune
🇮🇳
Pune, MAHARASHTRA, India
Dr. D.Y.Patil Dental College and Hospital,Pune
🇮🇳Pune, MAHARASHTRA, India
Dr Abhilasha Bhawalkar
Principal investigator
09860998482
abhilasha_bhawalkar@hotmail.com