A novel approach for the treatment of oral submucous fibrosi by injection pentoxyphylline and dexamethasone
Not Applicable
- Conditions
- Health Condition 1: K135- Oral submucous fibrosis
- Registration Number
- CTRI/2020/09/027836
- Lead Sponsor
- sharad pawar dental college wardha maharashtra
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1) Patients clinically diagnosed as having Grade II, III IV OSMF.
2) No obvious malignant disease in surroundings
Exclusion Criteria
1) Patient allergic or hypersensitive to the prescribed drugs. Patients who have previously exhibited intolerance to PTX or other xanthines such as caffeine, theophylline, etc.
2)Patient who have been treated with Intralesional injections/surgical modality.
3) Systemically compromised patients.
4) Pregnant or lactating mothers.
5) Patients with trismus of oral cavity due to reasons other than OSMF like TMJ ankylosis, Temporomandibular disorders, Myositis Ossificans etc.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method mouth openingTimepoint: every 1 month for 6 months
- Secondary Outcome Measures
Name Time Method Down staging of grading of Oral Submuacous fibrosisTimepoint: every 1 month for 6 months;Functional improvementTimepoint: every 1 month for 6 months;quality of lifeTimepoint: every 1 month for 6 months;reduction in burning sensationTimepoint: every 1 month for 6 months