to compare the efficiency of some herbal drugs in the treatment of amavata
- Conditions
- amavata ( rheumatoid arthritis)
- Registration Number
- CTRI/2017/12/010844
- Lead Sponsor
- National Institute of Ayurved
- Brief Summary
The clinical presentation of Amavata closely mimics with the special variety of Rheumatologic disorders called rheumatoid arthritis (R.A.). Prevalence of RA is approx. 0.8 % of the population. Due to wide spectrum of disease, much prevalence in the society and lack of effective medicine, the disease had been chosen for the study. Aim- To compare the efficacy of “Shiva Guggulu†and “Alambushadi Ghan Vati†in the management of Amavata (R.A.). Settings and Design: Single Centered, Open Labeled, Randomized Clinical Study. Methods and Material: 50 clinically diagnosed
patients of Amavata and who fulfilled the criteria of inclusion and willing to participate in trial were registered for present clinical trial and divided into two groups by simple randomization method (Lottery method). Group A- 25 patients of Amavata were administered ‘Shiva Guggulu’ 2 Tab (each Tab 500 mg.) thrice in a day with lukewarm water, after meal for 30 days Group B- 25 patients of Amavata were administered ‘Alambushadi Ghan Vati’ 2 Tab (each Tab 500 mg) thrice in a day, with lukewarm water, after meal for 30 days. Statistical analysis used: In Stat Graph Pad 3 Software was used for statistical analysis. For Nonparametric data Wilcoxon matched-pairs signed ranks test while for Parametric data Paired‘t’ Test and for Inter group comparison, Mann-Whitney Test & Unpaired ‘t’ Test were used. Conclusion: On comparing the effect of two therapies it can be concluded that Group B (Alambushadi Ghana Vati) provided better relief statistically than Group A (Shiva Guggulu) in most of the sign and symptom of the disease. It also considerably prevents the relapse.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 50
- The patients between the age group of 16 to 60 years in either sex presenting with clinical features of Amavata (R.A.).
- Pre-diagnosed patient of Amavata.
- (Chronicity < 4 years) 3.
- Patient willing to sign the consent forms.
- Patients having severe crippling bone deformities.
- Patients suffering from paralysis.
- Patients having any type of arthopathy such as neoplasm of spine, Gout, Ankylosing spondylosis, traumatic arthritis and pyogenic Osteomylitis etc.
- Patients having associated Cardiac disease, Tuberculosis, Diabetes Mellitus, Malignant Hypertension, Renal Function Impairment; Hypothyroidism, RHD etc.
- Patients with extremely reduced joint space.
- Pregnant women and lactating mother.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Patients of either sex 16-60 yr old diagnosed with amavata (rheumatoid arthritis) will be selected for relief in sign and symptoms 30 days
- Secondary Outcome Measures
Name Time Method Assess comparative efficacy of shiva gutika and alambushadi ghan vati in amavata (rheumatoid arthritis) 30 days
Trial Locations
- Locations (1)
National Institute of Ayurveda
🇮🇳Jaipur, RAJASTHAN, India
National Institute of Ayurveda🇮🇳Jaipur, RAJASTHAN, IndiaProf Ram Kishor JoshiPrincipal investigator9414322297joshirk1964@gmail.com