Cognitive Dysfunction in COPD Patients : Role in the Performance of Cognitive-motor Dual Task Situation?

Completed

• Conditions: Chronic Obstructive Pulmonary Disease
• Interventions: Other: Cognitive and motor performances

• Registration Number: NCT02493790
• Lead Sponsor: 5 Santé

Brief Summary

Chronic Obstructive Pulmonary Disease (COPD) is a respiratory disease starting point characterized by multiple systemic effects as cognitive dysfunction. This one seems to have an impact in activity daily living, considered mainly as a cognitive-motor dual task situations. Yet to date, no study has specifically focused in the cognitive-motor performance in patients with COPD or on the effects during a rehabilitation program. The main objective of this work was to evaluate the impact of cognitive dysfunction in COPD, comparing performance between COPD patients and healthy subjects in a single and dual task cognitive-motor situation. The secondary objective was to assess the impact of a rehabilitation program on these performances.

Detailed Description

Not available

Study Timeline

• Study Start: 2014-10
• Primary Completion: 2015-06
• Study First Submitted: 2015-06-30
• Study First Submitted QC: 2015-07-07
• Study First Posted: 2015-07-10
• Study Completion: 2016-08
• Status Verified: 2016-12
• Last Update Submitted: 2016-12-19
• Last Update Posted: 2016-12-20

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 45

Inclusion Criteria

• Male or female about 40 to 80 years old
• COPD patient (Tiffeneau <70%); stage moderate to severe (Stage 2,3 and 4) with or without oxygen therapy (>15h/day)
• Written and informed consent of the subject
• Authorization to physical activity referring doctor in the clinic
• Comorbidities no dominating

Exclusion Criteria

• Subject with neurological pathology, cognitive or psychiatric
• Subject with pain and / or plantar injuries
• Subject has a prosthetic knee and / or hip.
• Subject requiring walking aid (cane, walker, etc.)

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Volunteers	Cognitive and motor performances	Cognitive and motor performances were measured in a single and dual task situations.
COPD patients	Cognitive and motor performances	Cognitive and motor performances were measured in a single and dual task situations, before rehabilitation, and compared to those of healthy subjects. Then, Chronic Obstructive Pulmonary Disease patients were re-evaluated after rehabilitation.

Primary Outcome Measures

Name	Time	Method
Variability of motor performances in a single and dual task situations	3 months	Motor performance were determined by variability of length and surface of postural condition and by step variability in locomotion condition
Variability of Cognitive performances in a single and dual task situations	3 months	Cognitive performance were determined by error count and number of substraction during a counting task.

Secondary Outcome Measures

Name	Time	Method
Effect of rehabilitation program on Cognitive performances in a single and dual task	3 months	Comparison before and after rehabilitation program of counting task (number of substraction and error count)
Effect of rehabilitation program on motor performances in a single and dual task	3 months	Comparison before and after rehabilitation program of variability of length and surface of postural condition and step variability in locomotion condition