Efficacy Of Eggshell-derived Nanohydroxyapatite Graft For Bone Regeneration In Extracted Sockets - Randomized Control Study
试验速览
- 阶段
- 4 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 80
- 试验地点
- 1
- 主要终点
- 1.To assess bone regeneration in extracted sockets using egg shell derived nano hydroxyapatite and type 1 collagen using clinical, radiographic and histologiuc assessment
研究概览
简要总结
1.Efficiency of Egg shell derived Nano hydroxyapatite will be evaluated clinically by measuring the probing depth, wound dehiscence pre operatively and post operatively.
2.Changes in bone density, bone formation characteristics, lamina dura/ surgical/socket outline, bone fill at different time intervals will be evaluated radiographically by using pre operative and post operative intraoperative periodical radiograph and CBCT.
3.Wound healing will be assess by using Landry et al (1988)
4.Histology analysis will be carried out to evaluate bone formation at the grafted site. (For patients opting for implant placement, bone biopsy shall be done from the extraction site that was initially packed with eg shell derived nanohydroxyapatite.
5.To Evaluate any surgical site infection post Extraction.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 20.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients between 20 to 60 years of age.
- •Patients indicated for extraction of maxillary and mandibular teeth Patients willing for implants post placement of graft material in the socket.
排除标准
- •Patients with absolute contraindication for extraction.
- •Patients with systemic disorders Pregnant and lactating women Patients unwilling to participate in trail Patients allergic or sensitive to graft materials V or Type I collagen.
结局指标
主要结局
1.To assess bone regeneration in extracted sockets using egg shell derived nano hydroxyapatite and type 1 collagen using clinical, radiographic and histologiuc assessment
时间窗: 1.To assess bone regeneration in extracted sockets using egg shell derived nano hydroxyapatite and type 1 collagen using clinical, radiographic and histologiuc assessment during 1 week, 1 month , 3 months post operatively
次要结局
- 1.To assess bone formation in extracted sockets in patients grafted with & without egg shell derived nanohydroxyapatite(2.To assess wound healing in extracted sockets in patients grafted with & without egg shell derived nanohydroxyapatite using laundry healing index)
研究者
Dr Poonguzhali P
Sri Ramachandra Institute of Higher Education and Research