Impact of beta-lactamase detection reagent on rapid diagnosis of ESBL-producing pathogens

Not Applicable

• Conditions: rinary tract infection

• Registration Number: JPRN-UMIN000037140
• Lead Sponsor: Osaka General Medical Center

Brief Summary

In total, 350 urine samples were analysed. Urinary tract infection (UTI) was diagnosed in 214 patients. ESBL-producing Enterobacterales were isolated from 79 samples. The Cica-beta test showed sensitivity of 79.8% and specificity of 99.3% in patients with Gram-negative bacteriuria. Sensitivity and specificity improved to 90.2% and 100%, respectively, in patients with UTI.

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2019-06-23
• Study Completion: 2020-03-31
• Last Update Posted: 17 October 2023

Recruitment & Eligibility

• Status: Complete: follow-up complete
• Sex: All
• Target Recruitment: 350

Inclusion Criteria

Not provided

Exclusion Criteria

non

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Sensitivity and specificity of beta-lactamase detection reagent in detecting ESBL producing pathogens.

Secondary Outcome Measures

Name	Time	Method
1. Comparison of sensitivity and specificity among pathogens.