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临床试验/NCT04180787
NCT04180787已完成不适用

Effects of a Caffeine- and Protein-Containing Coffee Beverage on Metabolism and Muscular Performance

Texas Tech University2 个研究点 分布在 1 个国家目标入组 19 人开始时间: 2019年12月5日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
19
试验地点
2
主要终点
Isometric Force Production

研究概览

简要总结

The purpose of this randomized, double-blind, crossover study is to investigate the effects of Bang® Keto Coffee on resting and post-exercise metabolism and muscular performance during lower body resistance exercise.

详细描述

Resistance-trained males and females will be recruited for participation in a randomized, double-bind, crossover trial. After providing informed consent, each participant will undergo a familiarization session to become accustomed to the study procedures. Following familiarization, each participant will complete two laboratory visits consisting of metabolism and exercise performance assessments. In both visits, a baseline assessment of resting metabolic rate (RMR) and respiratory exchange ratio (RER) will be conducted using indirect calorimetry. Following the initial RMR assessment, each participant will ingest a coffee flavored beverage, either VPX Bang® Keto Coffee or a flavor-matched placebo. After beverage consumption, the participant will return to the supine position and rest prior to initiation of the second RMR assessment. Immediately following the second RMR assessment, the participant will begin a 5-minute dynamic bodyweight warm up. Participants will then begin squat testing procedures on a mechanized squat device. After completing the squat testing, participants will complete a standard 1-repetition maximum and repetitions to failure using a plate-loaded hip sled machine. Following the hip sled testing, participants will repeat the mechanized squat testing. Following completion of the exercise testing, a third and final RMR assessment will be performed. Following successful completion of the first condition, each participant will enter a wash out period, after which the visit will be repeated with ingestion of the alternative beverage.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Crossover
主要目的
Other
盲法
Triple (Participant, Investigator, Outcomes Assessor)

入排标准

年龄范围
18 Years 至 40 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • Between the ages of 18 and 40
  • Generally healthy (defined as an absence of any disease or medical condition which could potentially be negatively affected by consumption of the commercially available dietary supplement of performance of exercise, including but not limited to musculoskeletal or cardiovascular diseases).
  • Resistance-trained, defined as completing 3+ resistance training sessions per week for at least one year and including at least weekly training of the lower body through a multi-joint exercise such as the squat or leg press.
  • Regular caffeine consumption, defined as an average self-reported daily intake of 200+ mg of caffeine, which is equivalent to approximately 2 cups of coffee.

排除标准

  • Failing to meet any of the aforementioned inclusion criteria.
  • Pregnant or breastfeeding (for female participants)
  • Taking prescription medication which could reasonably make participation unsafe for the participant or influence study outcomes
  • An inability to complete lower body resistance exercise due to injury or medical condition
  • Self-reported caffeine sensitivity, as indicated by unwanted side effects when caffeine is consumed.
  • Allergy to any of the ingredients in the commercially available dietary supplement
  • Self-reported claustrophobia (due to metabolism testing)

结局指标

主要结局

Isometric Force Production

时间窗: Assessed approximately 80 minutes after beverage ingestion

Isometric force production on mechanized squat device

Isokinetic Force Production

时间窗: Assessed approximately 80 minutes after beverage ingestion

Isokinetic force production on mechanized squat device.

Maximal Lower Body Endurance

时间窗: Assessed approximately 75 minutes after beverage ingestion (following maximal lower body strength testing)

Repetitions to failure on hip sled machine

Change in Metabolic Rate

时间窗: Change in metabolic rate between: 1) before beverage ingestion (baseline) and 2) beginning approximately 5 minutes after completion of all exercise testing

Metabolic rate assessed via indirect calorimetry

Maximal Lower Body Strength

时间窗: Assessed approximately 75 minutes after beverage ingestion

One-repetition maximum on hip sled machine

Change in Respiratory Exchange Ratio

时间窗: Change in respiratory exchange ratio between: 1) before beverage ingestion (baseline) and 2) beginning approximately 5 minutes after completion of all exercise testing.

Respiratory exchange ratio as assessed via indirect calorimetry

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Sponsor

研究点 (2)

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