Ultrasonographic Evaluation of Talar Cartilage Thickness in Patients With Spinal Cord Injury: A Cross-Sectional Case-Control Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 76
- 试验地点
- 2
- 主要终点
- Talar cartilage thickness
研究概览
简要总结
Spinal cord injury patients often present with musculoskeletal comorbidities, including osteoarthritis. Early detection of cartilage damage is important for preventing osteoarthritis progression. This study aims to compare the talar cartilage thicknesses of spinal cord injury patients with healthy subjects. The secondary aim is to investigate a correlation between the talar cartilage thickness and disease-related parameters. The patient group is to be assessed for talar cartilage thickness (via ultrasound), functional status, spasticity, and ambulation levels.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Aged between 18 to 60 years,
- •Cervical, thoracal or lumber level of spinal cord injury
- •AIS (American Spinal Injury Association Impairment Scale) Level A, B, C, or D
- •Assisted ambulation of any kind
- •Giving oral and written consent to participate in the study
排除标准
- •Patients with sacral level injury
- •MAS 4 level of spasticity
- •History of any lower extremity operation
- •History of fracture
- •Botulinum toxin injection in the last 6 months
- •Existing diagnosis of any rheumatologic or endocrine diseases
研究组 & 干预措施
Control group
Age, sex, and BMI matched healthy controls
Patient group
Spinal cord injury patients
结局指标
主要结局
Talar cartilage thickness
时间窗: Baseline
The talar cartilage of both lower extremities are to be assessed with ultrasound
次要结局
- Functional Independence Measure (FIM) score(Baseline)
- Modified Ashworth Scale (MAS)(Baseline)
- Walking Index for Spinal Cord Injury II (WISCI II)(Baseline)