Obstructive Sleep Apnea Hypopnea Syndrome (OSAHS) and Transverse Orthodontic Deficiency in Children

Not Applicable

Not yet recruiting

• Conditions: Obstructive Sleep Apnea; Transverse Maxillary Deficiency

• Registration Number: NCT07086612
• Lead Sponsor: Fondation Hôpital Saint-Joseph

Brief Summary

OSAHS (Obstructive Sleep Apnea Hypopnea Syndrome) in children is a frequent respiratory disorder, whose prevalence is estimated at between 1.2 and 5.7%, and which, if left untreated, can cause severe medical complications. This prevalence tends to be underestimated. Diagnosis is made following a clinical examination noting the presence of characteristic clinical and polysomnographic criteria. Multidisciplinary management has been widely described in the literature, and various therapeutic options have been indicated. Rapid maxillary expansion has proved highly effective in the treatment of this condition. This syndrome is a real public health problem and must be diagnosed as early as possible. Through our research, we would like to study whether there is a causal link between an orthodontic problem of the transverse direction and the presence of SAHOS in children. In other words, we would like to assess whether children who clinically present an orthodontic deficiency of their transverse dimension are more likely to develop SAHOS than children without this deficit. If this proves to be true, then a new clinical sign could enable certain healthcare professionals to detect this syndrome early, and be able to refer patients to physicians as soon as possible.

Detailed Description

Not available

Study Timeline

• Status Verified: 2025-07
• Study First Submitted: 2025-07-18
• Study First Submitted QC: 2025-07-18
• Last Update Submitted: 2025-07-18
• Study First Posted: 2025-07-25
• Last Update Posted: 2025-07-25
• Study Start: 2025-08-01
• Primary Completion: 2026-09-01
• Study Completion: 2026-09-30

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 102

Inclusion Criteria

• Patient aged between 6 and 16 years
• Patients with a transverse orthodontic deficiency (group "CAS")
• Patients with another type of orthodontic deficiency (group "CONTROL") such as tooth rotation, crowding, mild Angle Class II or Class III dental occlusion
• Patient who has given free, informed oral consent
• Patient whose legal representatives have given their free written consent
• Patient affiliated with a health insurance scheme

Exclusion Criteria

• Patients refusing to participate in the study
• Patients whose legal representatives refuse to participate in the study

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Primary Outcome Measures

Name	Time	Method
study whether children with a transverse orthodontic deficiency have a higher risk of developing Obstructive Sleep Apnea Hypopnea Syndrome (OSAHS) compared to those without this deficiency,	1 months after enrollement	compare the proportion of children with an Apnea-Hypopnea Index (AHI) \>1, , based on the presence or absence of a transverse deficiency." AHI is evaluated with the polysomnography exam

Secondary Outcome Measures

Name	Time	Method
study whether all children with a transverse orthodontic deficiency systematically have Obstructive Sleep Apnea Hypopnea Syndrome (OSAHS)	one month after enrollement	distribution of Apnea-Hypopnea Index (AHI) values among these children
Investigate a link between the severity of this transverse deficiency and the severity of OSAHS.	1month after enrollement	Distribution of AHI values among children based on the extent of the transverse deficiency. Three groups will be formed for the transverse deficiency : one for pure endognathies, one for endoalveolies, and one for crossbite occlusions.".; AHI is evaluated with the polysomnography exam.
impact of hteSeverity of transferse deficiency on the snoring events frequency.	1months after enrollement	Average number of snoring events per hour based on the severity of the transverse deficiency. Three groups for the transverse defficiency will be formed: one for pure endognathies, one for endoalveolies, and one for crossbite occlusions.; Number of snoring event will be mesured by the polysomnography exam.
diagnostic value of the sleep disorder screening scale for children aged 4 to 16 years	1month after enrollement	comparison of the sleep disorder screening scale results with the results of the polysomnography exam.

Trial Locations

Locations (1)

Service d'orthopédie dento-cranio-maxillo faciale; 🇫🇷 Rouen, France