pedCAPNETZ - Community Acquired Pneumonia (CAP) in Childhood and Adolescence

• Conditions: Community-acquired Pneumonia

• Registration Number: NCT04047108
• Lead Sponsor: Hannover Medical School

Brief Summary

Establishment of a study network and patient cohort for pediatric CAP

Detailed Description

The aim of the project is the development of a large pediatric CAP patient cohort based on the established pedCAPNETZ pilot cohort. The main objective is to improve knowledge on etiology, epidemiology, diagnosis and management of pediatric CAP in a developed country. pedCAPNETZ will enable the systematic and detailed characterization of pediatric CAP cases on an epidemiological, clinical and biological level.

Study Timeline

• Study Start: 2014-12-18
• Study First Submitted: 2019-05-16
• Study First Submitted QC: 2019-08-05
• Study First Posted: 2019-08-06
• Status Verified: 2019-11
• Last Update Submitted: 2019-11-05
• Last Update Posted: 2019-11-06
• Primary Completion: 2023-12-31
• Study Completion: 2023-12-31

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 1000

Inclusion Criteria

• age < 18
• symptoms of an acute lower respiratory tract infection with radiological confirmed pneumonia via ultrasound or chest x-ray

Exclusion Criteria

• hospitalization for any reason within the last 28 days
• congenital or acquired immunodeficiency
• concomitant respiratory disease with impaired mucociliary clearance such as cystic fibrosis, primary ciliary dyskinesia, tracheostomy or other severe lung disease including pulmonary tuberculosis, malignancy, and cytostatic therapy during past 28 days or neutropenia (< 1000/µl) or relevant immunosuppressive treatment

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Number of patients with pediatric community acquired pneumonia (pedCAP) across all different levels of health care	5 years	To establish a multicenter national, prospective, observational and longitudinal pedCAP database and collaborative research network
Prevalence of pedCAP and etiologies (composite outcome measures) across all different levels of health care	5 years	* Etiology of pedCAP in Germany; * Clinical presentation of pedCAP; * Predictors of severe clinical course of pedCAP; * Diagnostics employed in management of pedCAP; * Microbiology and virology of pedCAP; * Radiology of pedCAP; * Comorbidity in patients with pedCAP; * Treatment patterns of pedCAP

Trial Locations

Locations (1)

Medizinische Hochschule Hannover; 🇩🇪 Hannover, Germany