Error-enhanced Learning & Recovery in 2 & 3 Dimensions
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 20
- 试验地点
- 2
- 主要终点
- Perpendicular Error
研究概览
简要总结
This study is being done to see how errors lead to improvement. Specifically, we are evaluating the errors stroke participants make during an upper extremity exercise program when reaching for a target using their affected arm. Once we understand the participant's reaching errors, we plan to create a customized reaching exercise according to the individual's specific error tendencies which will lead to better performance on movement ability after training.
详细描述
The neuroplasticity of motor re-learning is a key pathway for recovery in neurorehabilitation. One critical challenge to devising treatment plans for motor recovery is the wide variation that exists between individuals, across movement repetitions, and even within movements. Development of a learning model that looks at these factors would better relate diagnoses to treatments, providing personalization and efficiency to therapy. This proposal aims to advance rehabilitation by building a modeling framework that explores the trends and exploits a fundamental learning process - error. Our goal is to preliminarily test the direct effect of this new treatment in preparation for the randomized controlled study to come. Understanding how error leads to better performance will help us program future devices for therapy for optimal outcomes.
We are using research lab equipment at the Shirley Ryan AbilityLab (SRALab) Hospital's Robotics group. The equipment will be used to implement the reaching exercises and measure participant movement. The equipment includes:
- Barret b.u.r.t. arm robot with Teneo forearm attachment
- LookingGlass virtual reality display system
- Garmin Venu Sq fitness tracking wristwatch
Study Outline:
Week 1, Visit 1: Consent, In-Person Screening, and Baseline Evaluations Participants will sign a consent form. Then, they will undergo a screening process to check if they meet all the eligibility requirements. Participants that pass the in-person screening and agree to continue with the study will complete baseline evaluations which will consistent of upper extremity outcome measures, and a preliminary reaching experiment on the b.u.r.t. robotic arm.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Treatment
- 盲法
- Triple (Participant, Care Provider, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •18 years of age or older
- •Chronic stroke (8+ months post stroke event) with primary motor cortex involvement
- •Hemiparesis
- •Some degree of both shoulder and elbow movement capability
排除标准
- •Bilateral paresis
- •Severe tactile deficits using the Two-Point Discrimination Test (participant must detect<11mm)
- •Severe proprioceptive deficits
- •Severe spasticity (Modified Ashworth >3) preventing movement
- •Aphasia, cognitive impairment, or affective dysfunction that would influence the ability to perform the experiment
- •Visual deficits, and hemispatial neglect that would prevent the subjects from seeing the targets.
- •Inability to provide an informed consent
- •severe current medical problems
- •diffuse/multiple lesion sites or multiple stroke events
- •Inability to attain and maintain testing positions
- •Botox injection to the affected upper extremity within the previous 4 months
- •Concurrent participation in upper extremity rehabilitation either as part of a research intervention protocol or a prescribed therapy
- •Participation in previous, similar robotics intervention study
- •Other neurological issues
- •None of the following special populations will be included in this research study:
- •Adults unable to consent
- •Individuals who are not yet adults (infants, children, teenagers)
- •Pregnant women
- •Prisoners
- •Vulnerable Populations
研究组 & 干预措施
Group 1
干预措施: Error Fields (Other)
Group 1
干预措施: No Error Fields (Other)
Group 2
干预措施: Error Fields (Other)
Group 2
干预措施: No Error Fields (Other)
结局指标
主要结局
Perpendicular Error
时间窗: 60-90 minutes
次要结局
- Action Research Arm Test(5-20 minutes)
研究者
James Lanphier Patton
Co-Director, Robotics Laboratory, Arms and Hands Lab, Shirley Ryan AbilityLab
Shirley Ryan AbilityLab
