Autonomic Dysfunction in Patients With Pectus Excavatum.

• Conditions: Pectus Excavatum; Autonomic Dysfunction; Surgery
• Interventions: Procedure: Nuss surgery

• Registration Number: NCT03346876
• Lead Sponsor: Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation

Brief Summary

Investigators conducted a pilot study to to evaluate the autonomic function in participants with pectus excavatum before and after Nuss surgery.

Detailed Description

Since pectus excavatum can cause cardiac arrhythmia, the cardiac autonomic function in participants with pectus excavatum might be impaired. However, to our knowledge, there is no any study to evaluate the cardiac autonomic function in participants with pectus excavatum.

Study Timeline

• Status Verified: 2017-08
• Study Start: 2017-08-01
• Study First Submitted: 2017-11-15
• Study First Submitted QC: 2017-11-15
• Study First Posted: 2017-11-20
• Last Update Submitted: 2017-11-29
• Last Update Posted: 2017-11-30
• Primary Completion: 2018-07-31
• Study Completion: 2018-07-31

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 120

Inclusion Criteria

1. Clinical diagnosis of pectus excavatum
2. Agree to receive Nuss surgery to correct pectus excavatum

Exclusion criteria:

1. Major medical disease (asthma, heart failure, renal disease)
2. Known psychiatric disease
3. Known sleep-disordered breathing
4. Skeletal disease
5. Major surgery within 6 months

Exclusion Criteria

Not provided

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Study group	Nuss surgery	patients with pectus excavatum

Primary Outcome Measures

Name	Time	Method
The impact of Nuss surgery on HRV in patients with pectus excavatum	6 months	If Nuss surgery can improve HRV in different stress in patients with pectus excavatum?

Trial Locations

Locations (1)

Taipei Tzu-Chi Hospital, Buddhist Tzu-Chi Medical Foundation; 🇨🇳 New Taipei, Taiwan