NCT03366389已完成不适用
Evaluation of the Serum Levels of Apelin, Chemerin and Adiponectin Adipokines in Patients With Irritable Bowel Syndrome and Healthy Subjects
Amir Abbasnezhad1 个研究点 分布在 1 个国家目标入组 114 人开始时间: 2017年6月7日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 114
- 试验地点
- 1
- 主要终点
- Serum levels of Apelin, Chemerin and adiponectin
研究概览
简要总结
In this observational case-control study investigators aimed to assess the serum levels of adipokines such as Apelin, Chemerin and adiponectin in patients with irritable bowel syndrome (IBS), and compare it with healthy controls. Furthermore, investigators evaluated the possible correlation of these adipokines with IBS-QoL, IBSSS, GI symptoms and other clinical and psychological disorders.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Men and women between the ages of 18, and 80 years.
- •IBS patients diagnosed according to the Rome III Diagnostic Criteria for Functional GI Disorders.
排除标准
- •Any evidence of abdominal surgery or radiation
- •celiac disease, or other primary GI illnesses
- •GI infection obscuring IBS symptoms,
- •using total parenteral nutrition therapy in the last 6 months
- •pregnancy and lactation
- •alcohol consumption
- •concurrent chronic diseases such as diabetes, renal failure
- •diagnosed and/or treated malignancy in the past 5 years
- •anti-inflammatory drugs usage
- •intake of vitamin D, omega-3, vitamin E, and calcium supplements
- •being on a special diet or medication regimen during the last 6 months
结局指标
主要结局
Serum levels of Apelin, Chemerin and adiponectin
时间窗: in recruitment
次要结局
- Somatic Symptom(in recruitment)
- IBS-Quality of life (IBS-QoL)(in recruitment)
- IBS severity score system (IBSSS)(in recruitment)
- Gastrointestinal symptoms(in recruitment)
- Personality(in recruitment)
- Perceived Stress Scale(in recruitment)
研究者
Amir Abbasnezhad
Assistant Professor of Nutrition Science
Lorestan University of Medical Sciences
研究点 (1)
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