Pilot study of a ketogenic (low-carbohydrate) diet in patients receiving chemotherapy and radiation for glioblastoma multiforme (aggressive brain tumour)
Phase 2
Recruiting
- Conditions
- Glioblastoma multiformeCancer - Brain
- Registration Number
- ACTRN12614001056684
- Lead Sponsor
- Waikato District Health Board
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 20
Inclusion Criteria
* Patients with biopsy-proven glioblastoma multiforme who are considered suitable for standard chemoradiation (including adequate performance status and bone marrow, hepatic and liver function).
* Patients must be mentally competent to understand the requirements of the diet and believe that they, with the support of their carers, are capable of achieving them.
* Patients have given written informed consent
Exclusion Criteria
* Diabetic patients who are at risk of hypoglycaemic events (such as those on insulin or sulphonylureas)
* Current pregnancy or breast-feeding
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Progression-free survival [Eight months after starting chemoradiation]
- Secondary Outcome Measures
Name Time Method