Testing of BCG vaccine against COVID-19
- Conditions
- Coronavirus InfectionsAllied Health Personnel.J00-J99
- Registration Number
- RBR-4kjqtg
- Lead Sponsor
- niversidade Federal de Goias
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruitment completed
- Sex
- Not specified
- Target Recruitment
- Not specified
HW with BCG scar, adults, over 18 years old,who have negative IgM and IgG COVID-19 test, regardless of gender, dedicating at least 8 hours a week to care for individuals suspected of having COVID-19.
Participants with any of the following characteristics will be excluded: Individuals who have had a fever in the last 15 days; pregnant or lactating women; individuals with suspected viral infection including COVID-19 or bacterial in the past 15 days before randomization; have had a previous diagnosis of tuberculosis; has had a vaccination in the last 15 days; immunocompromised or with neutrophil count below 500 / mm3; using corticosteroids, antibiotics and chemotherapy drugs; present or have presented a solid or non-solid tumor in the last 2 years; or who are directly involved in the project.
Study & Design
- Study Type
- Intervention
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Reduction of health problems of health care workers related to COVID-19 among individuals vaccinated with BCG, verified by clinical evaluation and laboratory exames during 180 days.;Reduction of positivity for COVID-19 through serological, molecular tests and / or clinical evaluation among individuals vaccinated with BCG.
- Secondary Outcome Measures
Name Time Method innate immune response induction among individuals in the BCG vaccinated group, verified using citometric analysis of NK and neutrophils cell populations, 15-20 days after vaccination with BCG compared to day one (the day of inclusion in the study).<br>