A Prospective Multicenter Indian LMCA Registry

The left main coronary artery is distinguished by its larger diameter, broad distal bifurcation angle and the perfusion of a significant portion of the myocardium. The disease of LMCA are associated with the highest risk of morbidity and mortality among the subsets of coronary artery diseases with 70% damage to the myocardium when compared with other obstructive CADs.

Coronary artery bypass grafting (CABG) has traditionally been the gold standard for the management of patients with LMCA. However, percutaneous coronary intervention (PCI) has emerged as an alternative to CABG owing to its low periprocedural risk and continuous advancement in technology to provide better long-term outcomes and prognosis. Various systematic reviews and meta-analyses have documented clinical outcomes and long-term mortality among patients undergoing LMCA revascularization with CABG and PCI techniques. The drug-eluting stents have been a breakthrough in the PCI of LMCA and literature provides evidence on the safety and efficacy of using these stents in LMCA stenosis

There is a dearth of research on the clinical outcome of PCI for treating lesions in LMCA in India. Considering this, the data for the registry will be collected to assess the clinical outcomes of PCI with DES in patients with lesions in LMCA. This registry will be a prospective, multicentre, observational data collection study involving patients requiring PCI in LMCA.