Study of the Efficience of Chewing-gum to Reduce the Duration of Postoperative Ileus
- Conditions
- Postoperative Ileus
- Interventions
- Behavioral: chewing
- Registration Number
- NCT05296967
- Lead Sponsor
- University Hospital, Angers
- Brief Summary
Postoperative ileus (POI) is a serious complication after surgery. While it complicates all type of surgery, it is more frequent after abdominal surgery (especially bowel or colorectal surgery).
Many studies aim to reduce the occurence of POI without efficiency. The aim of this study is to assess the efficiency of the vagal stimulation, by the mean of chewing, to reduce the duration of POI.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 128
- patients undergoing colorectal surgery or small bowel surgery
- elective or in emergency
- open surgery or laparoscopy
- diagnosis of POI
- indication of fasting or nasogastric tube placement
- contra-indication of chewing
- pregnancy
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- CROSSOVER
- Arm && Interventions
Group Intervention Description Chewing gum chewing POI patients are asked to chew 20 minutes x2/ day
- Primary Outcome Measures
Name Time Method To assess the efficiency of chewing gum in reducing the duration of POI. POI is defined by the criteria of Vather from the postoperative day 1 up to day 30 collected each day until the end of the POI, assessed up to day 21 The duration of POI is the time between the first day of meeting the criteria of Vather to the day of recovery of tolerance of solid food and of exoneration of stool and/or flatus (GI-3 recovery).
Patients will be asked to report in their diary the day of tolerance of solid food and of exoneration of stool and/or flatus (GI-3 recovery) after the diagnosis of POI
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
University Hospital aof Angers
🇫🇷Angers, France