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A clinical trial comparing daily versus intermittent vitamin D supplementation in children with nephrotic syndrome

Phase 3
Conditions
Health Condition 1: N049- Nephrotic syndrome with unspecified morphologic changes
Registration Number
CTRI/2020/04/024598
Lead Sponsor
Jawaharlal Nehru medical college
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Closed to Recruitment of Participants
Sex
Not specified
Target Recruitment
0
Inclusion Criteria

Children in the age group of <14 years diagnosed as SDNS/FRNS, who have serum vitamin D levels of > 20 ng/dL, shall be considered for enrolment in this trial.

Exclusion Criteria

1. Age more than 14 years or <1year

2. Refusal to give consent

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
umber of patients who remain vitamin D sufficient with 2 monthly vitamin D supplementationTimepoint: At 1 year of supplementation
Secondary Outcome Measures
NameTimeMethod
Differences in bone health <br/ ><br>Timepoint: At 1 year follow up;Differences in serum levels of vitamin D, calcium, PTH and phosphorusTimepoint: At 1 year follow up;relapse frequency and rate of infectionTimepoint: 2 monthly for 1 year;Adverse effects of vitamin DTimepoint: 4 monthly for 1 year;changes in BMI and HeightTimepoint: 2 monthly for 1 year
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