NCT03041662已完成不适用
Surveillance Study for Early Detection of Cholangiocarcinoma (CCA) in Primary Sclerosing Cholangitis (PSC)
Karolinska University Hospital1 个研究点 分布在 1 个国家目标入组 620 人开始时间: 2011年10月31日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 620
- 试验地点
- 1
- 主要终点
- death
研究概览
简要总结
This observational study of a national cohort of 600 Swedish PSC patients include yearly MR/MRCP, biobanking of serum, plasma and blood, followup clinical data (interventions, symptoms, labs, colonoscopy). The aim is to collect a well characterized cohort of PSC patients and provide future possibilities to evaluate biomarkers for prognosis and early cancer detection.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Diagnosis of PSC by MR/MRCP
- •Life expectancy >1 year
- •Informed consent
排除标准
- •Liver transplantation or on the waiting list
- •Secondry SC
- •Diagnosis of CCA
结局指标
主要结局
death
时间窗: 10 yrs f-up
death
cholangiocarcinoma
时间窗: 10 yrs f-up
cholangiocarcinoma
liver transplatation
时间窗: 10 yrs f-up
liver transplatation
次要结局
- biliary dysplasia(10 yrs f-up)
研究者
Annika Bergquist
professor
Karolinska University Hospital
研究点 (1)
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