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ELIAS: Early Loop-Recorder in Suspected Arrhythmogenic Syncope

Phase 4
Completed
Conditions
Syncope
Registration Number
NCT00170261
Lead Sponsor
Medtronic Bakken Research Center
Brief Summary

This is a prospective, controlled, opened randomized study to evaluate the cost benefit of a primary implantation of a loop recorder versus the conventional diagnostic cascade for syncope most likely due to cardiac arrhythmia.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
100
Inclusion Criteria
  • Two or more episodes of syncope (most likely due to cardiac arrhythmia) of uncertain etiology within the last 12 months or more than one syncope and two presyncopes
Exclusion Criteria
  • Indication for the implantation of a pacemaker
  • Indication for the implantation of an implantable cardioverter defibrillator
  • Cardiac diseases which need intervention (KHK, aortic stenosis, mitral stenosis, left ventricular [LV] outflow stenosis, decompensated heart failure)
  • Contraindication for a diagnostic procedure requested by the study protocol
  • Enrollment in another study
  • Circumstances or comorbidities which do not allow enrollment

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Primary Outcome Measures
NameTimeMethod
Cost of diagnostics per patient until final cardiac diagnosis has been made
Secondary Outcome Measures
NameTimeMethod
Cost of diagnostics until final diagnosis has been made
Rate of correct cardiac diagnoses
Comparison of time needed to make a diagnosis
Comparison of pre-syncopes and syncopes occuring in both groups after enrollment

Trial Locations

Locations (3)

Humbold Klinikum

🇩🇪

Berlin, Germany

Vivantes Klinikum am Urban

🇩🇪

Berlin, Germany

Universitätsklinikum Hamburg Eppendorf

🇩🇪

Hamburg, Germany

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