Study of technologies for the diagnosis of angle closure glaucoma

Not Applicable

• Conditions: Angle-closure glaucoma; Eye Diseases

• Registration Number: ISRCTN15115867
• Lead Sponsor: Queen's University Belfast

Brief Summary

2023 Protocol article in https://pubmed.ncbi.nlm.nih.gov/37793921/ (added 05/10/2023)

Detailed Description

Not available

Study Timeline

• Study Start: 2023-03-10
• Last Update Posted: 12 August 2024
• Study Completion: 2024-12-31

Recruitment & Eligibility

• Status: Ongoing
• Sex: All
• Target Recruitment: 600

Inclusion Criteria

Adults (=18 years) referred from community optometry to hospital eye services with suspected angle closure glaucoma

Exclusion Criteria

Unable to provide informed consent

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Sensitivity and specificity of the new pathway to detect angle-closure glaucoma measured using standard formulas and pre-specified criteria for test positivity. All tests will be done at the same clinic visit.

Secondary Outcome Measures

Name	Time	Method
The following outcome measures will be assessed and recorded in patient notes at the same clinic visit:<br>1. Positive/negative likelihood ratios for angle-closure glaucoma development measured using standard formulas<br>2. Concordance measured using standard formulas<br>3. Long-term health and cost outcomes measured using a Markov model run over an expected lifetime time horizon<br>4. Proportion of patients requiring subsequent clinical assessment by ophthalmologist measured using descriptive statistics<br>5. Proportion of patients unable to undergo tests and of tests of inadequate quality measured using descriptive statistics<br>6. Health-related quality of life measured using the EuroQol Health Questionnaire (EQ-5D-5L)