Study of technologies for the diagnosis of angle closure glaucoma
Not Applicable
- Conditions
- Angle-closure glaucomaEye Diseases
- Registration Number
- ISRCTN15115867
- Lead Sponsor
- Queen's University Belfast
- Brief Summary
2023 Protocol article in https://pubmed.ncbi.nlm.nih.gov/37793921/ (added 05/10/2023)
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Ongoing
- Sex
- All
- Target Recruitment
- 600
Inclusion Criteria
Adults (=18 years) referred from community optometry to hospital eye services with suspected angle closure glaucoma
Exclusion Criteria
Unable to provide informed consent
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Sensitivity and specificity of the new pathway to detect angle-closure glaucoma measured using standard formulas and pre-specified criteria for test positivity. All tests will be done at the same clinic visit.
- Secondary Outcome Measures
Name Time Method The following outcome measures will be assessed and recorded in patient notes at the same clinic visit:<br>1. Positive/negative likelihood ratios for angle-closure glaucoma development measured using standard formulas<br>2. Concordance measured using standard formulas<br>3. Long-term health and cost outcomes measured using a Markov model run over an expected lifetime time horizon<br>4. Proportion of patients requiring subsequent clinical assessment by ophthalmologist measured using descriptive statistics<br>5. Proportion of patients unable to undergo tests and of tests of inadequate quality measured using descriptive statistics<br>6. Health-related quality of life measured using the EuroQol Health Questionnaire (EQ-5D-5L)