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Beer or Ethanol Effects on the Response to High Intensity Interval Training: A Controlled Study in Healthy Individuals

Not Applicable
Completed
Conditions
Drinking, Alcohol
Exercise
Interventions
Other: HIIT-AB Group
Other: HIIT-ASW Group
Other: HIIT-SW Group
Other: HIIT-NAB Group
Registration Number
NCT03660579
Lead Sponsor
Universidad de Granada
Brief Summary

HIIT-BEER will determine the effect of habitual and moderate beer intake (330-660 ml / day, 5 days / week) on physical fitness, body composition, psychokinetic abilities and psychological status in sedentary healthy adults undergoing a HIIT training program.

Detailed Description

Aims:

To determine the effect of habitual and moderate consumption of beer on physical fitness, body composition, psychokinetic and cognitive abilities and psychological status in sedentary healthy adults undergoing a HIIT training program.

The primary hypothesis will that a HIIT program will induce an improvement on physical fitness, body composition, psychokinetic abilities and psychological responses compared to a control group but this positive effect could be blunted by alcohol intake.

Methods:

HIIT-BEER will recruit 80 sedentary, healthy, adults (50% women) aged 18-40 years.

Will be performed a 10-week controlled trial in which the effects of HIIT will be compared to a control group without training. The effects of habitual intake of different alcoholic beverage will be also compared.

After completing the baseline measurements, the selected participants will be randomly assigned to either the control or the exercise training groups. The participants included in the training groups will be asked to choose individual choice about their drinking preference for alcoholic or non-alcoholic beverages. The participants who chose alcohol intake will be randomly assigned into the training group with alcohol beer intake (5.4% Alcohol-Special Alhambra®, Cervezas Alhambra, Spain) or to the sparkling water group with exactly the same amount of distilled alcohol added. The distilled alcoholic beverage used for the investigator's study will be vodka because of the purity of its composition (37.5% ethanol and 62.5% water). The participants who chose non-alcoholic beverages will be randomized into the training groups of non-alcohol beer (0.0% alcohol-Cruzcampo®, Heineken España) or sparkling water (Eliges (IFA) Eliqua 2®, Font Salem, Spain) intakes.

So, eligible participants will be assigned to five groups: (i) a group that will performed HIIT and will consumed 330 ml (women) or 2x300 ml (men) of beer with 5.4% alcohol (HIIT-AB, n=16); (ii) a group that will performed HIIT and will consumed the same amount of beer without alcohol (0.0%) (HIIT-NAB; n=16); (iii) a group that will performed HIIT and will consumed the same amount of sparkling water (0.0%) (HIIT-W; n=16); (iv) a group that will performed HIIT and will consumed sparkling water with the same amount of alcohol than the pre-established beer (5.4%) (HIIT-ASW; n=16); and (v) a control group that will not perform any physical training program (CON; n=16).

The beverage intakes will be programmed from Monday to Friday. There will not specific recommendation for Saturday and Sunday, but the participants will be instructed to keep a moderate alcohol during the weekend.

Laboratory measures completed at baseline and 10 weeks later, include physical fitness (cardiorespiratory fitness, muscular strength), body composition, hearth rate variability (HRV), reaction time, cognitive variables and health-related questionnaires. The investigators will also obtain dietary habits data and cardiovascular disease risk factors.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
80
Inclusion Criteria
  • Age: 18-40 years
  • BMI:18.5-25 kg/m2
  • Not engaged in regular physical activity >20min on >3days/week
  • Not participating in a weight loss programme
  • Stable weight over the last 5 months (body weight changes>5kg)
  • Participant must be capable and willing to provide consent, understand exclusion criteria and accept the randomized group assignment
  • Normal electrocardiogram
  • Not personal family history related to alcohol consumption.
Exclusion Criteria
  • History of cardiovascular disease
  • Diabetes
  • Pregnancy or planning to get pregnant during study period
  • Beta blockers or benzodiapezins use
  • Taking medication for thyroid
  • Other significant conditions that are life-threatening or that can interfere with or be aggravated by exercise
  • Unwillingness to either complete the study requirements or to be randomized into control or training group

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
HIIT-AB GroupHIIT-AB GroupIntake: 330ml (women) or 2x300 ml (men) of beer with 5.4% alcohol. The beverage intakes will be programmed from Monday to Friday. Training: The volume in HIIT 40-65 min/week at high intensity. HIIT with short intervals. Frequency two times/week. Load variation. Gradual progression to control the exercise dose. Periodization divided in: familiarization phase, phase I, phase II. Sessions. The participants will performed 8 weight-bearing exercises (in circuit form) 2 times/set with an active rest (walking at 6 RPE scale) as many times at as defined. The HIIT intensity will controlled by RPE (0-10 RPE scale). All sessions will be started with a dynamic standardized warm-up, including several muscle activation exercises, and will be ended with a cooling-down protocol.
HIIT-ASW GroupHIIT-ASW GroupIntake: 330 ml (women) or 2x300 ml (men) of sparkling water with 5.4% alcohol.The beverage intakes will be programmed from Monday to Friday. Training: The volume in HIIT 40-65 min/week at high intensity. HIIT with short intervals. Frequency two times/week. Load variation. Gradual progression to control the exercise dose. Periodization divided in: familiarization phase, phase I, phase II. Sessions. The participants will performed 8 weight-bearing exercises (in circuit form) 2 times/set with an active rest (walking at 6 RPE scale) as many times at as defined. The HIIT intensity will controlled by RPE (0-10 RPE scale). All sessions will be started with a dynamic standardized warm-up, including several muscle activation exercises, and will be ended with a cooling-down protocol.
HIIT-SW GroupHIIT-SW GroupIntake: 330 ml (women) or 2x300 ml (men) of sparkling water. The beverage intakes will be programmed from Monday to Friday. Training: The volume in HIIT 40-65 min/week at high intensity. HIIT with short intervals. Frequency two times/week. Load variation. Gradual progression to control the exercise dose. Periodization divided in: familiarization phase, phase I, phase II. Sessions. The participants will performed 8 weight-bearing exercises (in circuit form) 2 times/set with an active rest (walking at 6 RPE scale) as many times at as defined. The HIIT intensity will controlled by RPE (0-10 RPE scale). All sessions will be started with a dynamic standardized warm-up, including several muscle activation exercises, and will be ended with a cooling-down protocol.
HIIT-NAB GroupHIIT-NAB GroupIntake: 330 ml (women) or 2x300 ml (men) of beer without alcohol (0.0%). The beverage intakes will be programmed from Monday to Friday. Training: The volume in HIIT 40-65 min/week at high intensity. HIIT with short intervals. Frequency two times/week. Load variation. Gradual progression to control the exercise dose. Periodization divided in: familiarization phase, phase I, phase II. Sessions. The participants will performed 8 weight-bearing exercises (in circuit form) 2 times/set with an active rest (walking at 6 RPE scale) as many times at as defined. The HIIT intensity will controlled by RPE (0-10 RPE scale). All sessions will be started with a dynamic standardized warm-up, including several muscle activation exercises, and will be ended with a cooling-down protocol.
Primary Outcome Measures
NameTimeMethod
Physical Fitness Cardiorespiratory fitnessBaseline and through study completion, an average of 10 weeks.

Cardiorespiratory fitness measure through a maximum treadmill test (VO2 max.).

Secondary Outcome Measures
NameTimeMethod
Physical Fitness: Muscular strength (Bosco Test)Baseline and through study completion, an average of 10 weeks.

Muscle strength measure through: Bosco test.

Physical Fitness: Muscular strength (Handgrip strength)Baseline and through study completion, an average of 10 weeks.

Muscle strength measure through: Handgrip strength.

Body composition (DXA)Baseline and through study completion, an average of 10 weeks.

Body composition measure through: Dual-energy X-ray absorptiometry (DXA).

Body composition (Weight)Baseline and through study completion, an average of 10 weeks.

Body composition measure through: Anthropometry (Weight in kg).

Body composition (Height)Baseline and through study completion, an average of 10 weeks.

Body composition measure through: Anthropometry (Height in meter).

Body composition (Hip perimeter)Baseline and through study completion, an average of 10 weeks.

Body composition measure through: Anthropometry (Hip perimeter in cm)

Body composition (Waist circumference)Baseline and through study completion, an average of 10 weeks.

Body composition measure through: Anthropometry (Waist circumference in cm).

Body composition (Neck perimeter)Baseline and through study completion, an average of 10 weeks.

Body composition measure through: Anthropometry (Neck perimeter in cm).

Heart Rate VariabilityBaseline and through study completion, an average of 10 weeks.

Measure by Polar RS800CX.

Reaction timeBaseline and through study completion, an average of 10 weeks.

Measure by Vienna Test System.

MemoryBaseline and through study completion, an average of 10 weeks.

Measure by Spanish-Complutense Verbal Learning Test (TAVEC)

AttentionBaseline and through study completion, an average of 10 weeks.

Measure by D2 Test.

Working MemoryBaseline and through study completion, an average of 10 weeks.

Measure by Numbers and Letters (WISC-IV).

Verbal fluencyBaseline and through study completion, an average of 10 weeks.

Verbal fluency assessment test.

Questionnaires and ScalesEvery three weeks

Measure by:

Scale of Subjective Happiness; Pittsburgh Sleep Quality Index; POMS; BREQ-2 and GOES.

Questionaires and ScalesEvery two weeks

Measure by:

PSS; EVEA; PANNAS; TMMS-24

Trial Locations

Locations (1)

Universidad de Granada

🇪🇸

Granada, Andalucia, Spain

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