Maternal and fetal serum levels of DKK-1 and the placental expression of ß-Catenin in pre-eclamptic and normal pregnancies as well as the postpartal observation of sFlt-1/PlGF ratio and its correlation with clinical and biochemical courses.
Recruiting
- Conditions
- O14Pre-eclampsia
- Registration Number
- DRKS00006526
- Lead Sponsor
- niversitätsklinikum des Saarlandes
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Female
- Target Recruitment
- 30
Inclusion Criteria
Diagnosis of Preeclampsia. Control: Normal pregnancies.
Exclusion Criteria
Below 16 years of age.
Maternal underlying chronic diseases.
No signing of consent.
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method prepartal and postpartal serum sFlt-1/PlGF ratio course in postpartal patients with pre-eclampsia. <br>serum DKK-1, ß-Catenin Placental Expression in pre-eclamptic pregnancies.
- Secondary Outcome Measures
Name Time Method Difference between mild and severe pre-eclampsia regarding biomarkers (DKK1, ß-Catenin and postpartal markers: sFlt-1/PlGF)