Study on the Efficacy of Vetiver Essential Oil Aroma on Depression/Anxiety People
试验速览
- 阶段
- 不适用
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- The measure blood pressure (SBP and DBP)
研究概览
简要总结
In this study, subjects with depression/anxiety inhaled the essential oil, which contained sedative, soothing, and relaxing active ingredients to stimulate the olfactory nerve. The essential oil further transmitted to the limbic system that controls emotions in the brain, and then affected the human's mood. The natural aroma can not only awaken the limbic system's memory of aroma but also reflect the subconscious area of the brain, with physiological changes (such as controlling blood pressure, breathing, heartbeat, stress changes, memory, and hormonal coordination.) This study monitors the subject's autonomic nerve parameters before and after aromatherapy to obtain the olfactory cerebral nervous system to convey the message. When the study finishes, we expected to help the subject to relax and soothe the mind.
详细描述
Subjects receive three times 30 mins aromatherapy of Limon or Vetiver essential oil per time for the month. Anthropometric measurements such as blood pressure (systolic blood pressure [SBP] and diastolic blood pressure [DBP]), autonomic nerve parameters including a. SDNN (standard deviation of all normal to normal intervals index); b. HRV（heart rate variability）; c. LF（0.04-0.15 Hz）and HF（0.15-0.4 Hz）were measured every week. PSQI（Pittsburgh sleep quality index）and HADS (Hospital Anxiety and Depression Scale) were measured initial and ten ends.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 20 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Depressed/anxious people (diagnosed as a single episode of major depression, recurrence of major depression, mild depression, panic disorder, and anxiety.) Those diagnosed with symptoms of depression, and anxiety related to stress adjustment disorder, and willing to cooperate with the study.
- •Age 20-65 years old
排除标准
- •an alcoholic
- •Uncontrolled diabetes
- •Those who have had a stroke in the last year
- •Pregnant and lactating women
- •People with liver or heart disease
- •Arrhythmia or those with a heart rhythm regulator
- •Those whose heart has already been fitted with a cardiac catheter stent
- •Those who have used central nervous system stimulants (regardless of the length of time)
- •Those who are allergic to essential oils
- •Those who have used aromatherapy within a month
- •Subjects request to withdraw from the trial
- •The host feels unsuitable to continue the study
结局指标
主要结局
The measure blood pressure (SBP and DBP)
时间窗: one month
values change of systolic and diastolic BPs
The aromatherapy measure autonomic nerve parameter SDNN (standard deviation of all normal to normal intervals index)
时间窗: one month
次要结局
未报告次要终点
研究者
You-Cheng Shen
Associate Professor
Chung Shan Medical University