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Clinical Trials/PACTR202201638897606
PACTR202201638897606
Not yet recruiting
Phase 2

Intervention to optimise change in BMI of adolescent pre-conception to address the double burden of malnutrition: An RCT in rural and urban South Africa

Wits Health Consortium University of the Witwatersrand0 sites1,248 target enrollmentFebruary 2, 2021

Overview

Phase
Phase 2
Intervention
Not specified
Conditions
Nutritional, Metabolic, Endocrine
Sponsor
Wits Health Consortium University of the Witwatersrand
Enrollment
1248
Status
Not yet recruiting
Last Updated
2 years ago

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
February 2, 2021
End Date
TBD
Last Updated
2 years ago
Study Type
Interventional
Sex
Female

Investigators

Sponsor
Wits Health Consortium University of the Witwatersrand

Eligibility Criteria

Inclusion Criteria

  • Adolescent girls and young women who are underweight (defined as BMI \< 9th percentile for age by the WHO 2007 international reference) (BMI \> 91st percentile)
  • \-overweight/obese (defined as BMI \> 91st percentile for age by the WHO 2007 international reference)
  • \-Adolescent girls and young women aged 14\-19 years
  • \-HIV negative
  • \-in school grades 8\-11
  • \-Adolescent girls and young women who are nulliparous
  • \- Presence of a primary female caregiver of the index adolescent participant resident in the same household

Exclusion Criteria

  • \-Girls with Type\-1 diabetes
  • \-Previously identified severe intellectual disability
  • \-Evidence of severe depression based on a PHQ9 score of 20 and above (PHQ9 is used extensively in South Africa to monitor the severity of depression)
  • \-Adolescents screened HIV positive (However, they will be invited to participate in a sub\-study and receive the intervention arm components, to provide important formative insights on a special population).

Outcomes

Primary Outcomes

Not specified

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