Skip to main content
Clinical Trials/CTRI/2025/07/092009
CTRI/2025/07/092009
Not yet recruiting
Phase 4

Comparative evaluation of Laser Biostimulation and LED Photoactivation using Methylene Blue in the Treatment of Periodontitis: A split-mouth randomized controlled trial

Dr Poojitha Koppada1 site in 1 country112 target enrollmentStarted: August 25, 2025Last updated:

Overview

Phase
Phase 4
Status
Not yet recruiting
Sponsor
Dr Poojitha Koppada
Enrollment
112
Locations
1
Primary Endpoint
Probing pocket depth

Overview

Brief Summary

The title of the study is Comparative evaluation of LASER biostimulation and LED photoactivation using methylene blue in the treatment of periodontitis A split mouth randomized controlled trial. A total of 112 sites from periodontitis patients satisfying the inclusion and exclusion criteria and providing consent for study participation will be selected and split into two groups. Group 1 will be allocated with 56 sites and will be receiving Laser biostimulation adjunct to scaling and root planing with the biostimulation at 1st,15th,30th and 45th day. Group 2 with 56 sites and will be receiving LED photoactivation using methylene blue adjunct to scaling and root planing with the activation at 1st,15th,30th and 45th day. The clinical parameters such as Bleeding on probing, Plaque index, Probing pocket depth  and clinical attachment loss will be evaluated and compared in both the groups pre operatively and 2 months post operatively.

Study Design

Study Type
Interventional
Allocation
Coin toss, Lottery, toss of dice, shuffling cards etc
Masking
Outcome Assessor Blinded

Eligibility Criteria

Ages
25.00 Year(s) to 55.00 Year(s) (—)
Sex
All

Inclusion Criteria

  • Subjects with the age group between 25 – 55 years old Subjects with stage II periodontitis 5mm Systemically healthy subjects Subjects with good compliance.

Exclusion Criteria

  • Subjects with systemic diseases and conditions Subjects who underwent periodontal treatment within 6 months prior to the study Smokers and tobacco users Pregnant or lactating women.

Outcomes

Primary Outcomes

Probing pocket depth

Time Frame: To evaluate and compare Probing pocket depth and Clinical attachment loss 2 months

Clinical attachment loss at 2 months

Time Frame: To evaluate and compare Probing pocket depth and Clinical attachment loss 2 months

Secondary Outcomes

  • Plaque index(Bleeding on probing at 2 months)

Investigators

Sponsor
Dr Poojitha Koppada
Sponsor Class
Other [Self funded]
Responsible Party
Principal Investigator
Principal Investigator

Dr Poojitha Koppada

GITAM Dental College and Hospital

Study Sites (1)

Loading locations...

Similar Trials