Comparing the Effectiveness of Daily VS Every other day of Oral Astaxanthin on Improvement Skin Elasticity, A Randomized, Double-blind Clinical Trial
- Conditions
- Healthy women and elasticity
- Registration Number
- TCTR20210321001
- Lead Sponsor
- one
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending (Not yet recruiting)
- Sex
- Female
- Target Recruitment
- 40
1. Female 2. age 30-45 year old 3. BMI 18.5-29.9 4. No underlying disease 5. No menopause condition 6. Have the intention of participating in the project from start to finish. And able to come and monitor every time in research work 7. No behavior or the use of oral drugs or injections that affect the absorption of Astaxanthin such as smoking 8. No history of hypersensitivity to any of the researched supplements such as soybean oil 9. Not a skin disease such as allergic rash, inflammation, acne in the area to be tested. 10. Do not change intake of dietary supplements, or not intake drugs that affect skin conditions, such as isotretionin, tranexamic acid, during the test. 11. The ablative, semi-ablative laser was not performed 3 months prior to the test. 12. Did not do HIFU for 6 months prior to the test. 13. Ulthera thermage was not performed 12 months prior to the test. 14. Botulinum toxin has not been injected at the site to be tested for 6 months prior to the test. 15. Do not inject fillers or stem cells in the area to be tested within 1 year before testing. 16. Not during pregnancy or breastfeeding.
1. Get pregnant during the test 2. Forget to take supplements for more than two consecutive days or more than four days per 2 weeks 3. There have been botulinum toxin, filler injections or laser during testing. 4. Use new creams during the experiment or stop using the old product. 5. There have been changes in the behavior of taking vitamins or other dietary supplements, such as eat more or stop eating things you eat regularly during the test. 6. There is an increase in stress during the test. For example, moving home, having trouble sleeping, etc. 7. Volunteers withdraw from the study.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Skin elasticity Cutometer Cutometer
- Secondary Outcome Measures
Name Time Method Skin hydration week 0, 8 Corneometer,Transepidermal water loss week 0, 8 TEWAmeter,Melanin index week 0, 8 Mexameter