Retrospective Study of Myocardial Damage in COVID-19
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 500
- 试验地点
- 1
- 主要终点
- The myocardial injury incidence
研究概览
简要总结
This study aims to investigate the clinical characteristics, the incidence of myocardial injury, and the influence of myocardial injury on the prognosis in COVID-19 patients. There is no additional examination and treatment for this project.
详细描述
The epidemic of the COVID-19 has expanded from Wuhan through out China, and is being exported to a growing number of countries. Recently, investigators have revealed that acute myocardial injury is existed in 7.2% patients with COVID-19, and this proportion in patients admitted to the ICU (22.2%) is higher than patients not treated in the ICU (2.0%). Thus, cardiac troponin I (cTNI), the biomarker of cardiac injury, might be a clinical predictor of COVID-19 patient outcomes. This study aims to investigate the clinical characteristics, the incidence of myocardial injury, and the influence of myocardial injury on the prognosis in COVID-19 patients.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •(1) Age ≥18 years. (2) Laboratory (RT-PCR) confirmed infection with SARS-CoV-
- •(3) Lung involvement confirmed with chest imaging.
排除标准
- •No cTnI test on admission
结局指标
主要结局
The myocardial injury incidence
时间窗: 75 days
The myocardial injury incidence of COVID-19 patients
The risk factors analysis for the death
时间窗: 75 days
The risk factors analysis for the death of COVID-19 patients
次要结局
- Clinical course(75 days)
- Cardiovascular comorbidity(75 days)
- Clinical characteristics(75 days)
- Analysis of causes of death(75 days)
研究者
Xiang Cheng
Professor
Wuhan Union Hospital, China