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Biofeedback Based Virtual Reality Intervention to Manage Postoperative Pain

Not Applicable
Conditions
Pain, Postoperative
Pain
Pain, Acute
Surgery
Interventions
Device: Technology Based Intervention Group 1
Device: Technology Based Intervention Group 2
Registration Number
NCT04943874
Lead Sponsor
Vanessa Olbrecht
Brief Summary

To develop and refine a technology based treatment protocol for preoperative education and training and postoperative care in children and adolescents undergoing surgery.

Detailed Description

This is a 2-phase study aimed to refine a perioperative treatment protocol for a technology-based intervention (Aim 1) and to understand whether technology-based interventions can be used to help treat pain in children following surgery (Aim 2). Patients will participate in only one phase of the study, and when patients are enrolled will determine what Phase of the study they are in.

In Phase 1, all patients will use the same technology, and no randomization will occur. Primary and secondary outcome measures of Aim 1 are assessed in Phase 1. Actual enrollment for Phase 1 was 23 patients.

In Phase 2, patients will be randomized to receive 1 of 2 technology-based interventions. The perioperative treatment protocol developed in Phase 1 (Aim 1) will be used in Phase 2 to assess the primary and secondary outcome measures of Aim 2. This phase is anticipated to enroll up to 70 participants.

This is not an FDA-regulated drug or device trial as the technology used in this study is categorized as a relaxation device by the FDA and considered "minimal risk", thus exempt from both NDE and IDE.

Recruitment & Eligibility

Status
ENROLLING_BY_INVITATION
Sex
All
Target Recruitment
93
Inclusion Criteria
  • Ages 12 -18 years
  • Scheduled to undergo surgery anticipated to cause moderate to severe pain with expected length of stay > or = to 2 days
  • Able to read, understand and speak English
  • Patients requiring management by the Acute Pain Service
  • Possession of a mobile device/computer available for study participation
Exclusion Criteria
  • Outside the age range (< 12 or > 18 years)
  • Non-English speaking
  • History of significant developmental delay, uncontrolled psychiatric conditions associated with hallucinations or delusions, or neurological conditions (especially epilepsy and/or significant motion sickness/nausea/vomiting)
  • History of vertigo, dizziness, seizure disorder, and/or severe motion sickness
  • History of chronic pain
  • Are chronically using opioids and or benzodiazepines for the management of pain
  • Are actively experiencing nausea or vomiting
  • Conditions such as craniofacial abnormalities or surgeries of the head and neck
  • Previous participation in this study

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Technology Based Intervention 1 (Phase 1)Technology Based Intervention Group 1-
Technology Based Intervention 2 (Phase 2)Technology Based Intervention Group 2-
Technology Based Intervention 1 (Phase 2)Technology Based Intervention Group 1-
Primary Outcome Measures
NameTimeMethod
Aim 1: Treatment protocol refinementDuration of study up to 30 days

Duration of sessions

Aim 2: Feasibility of technology intervention in perioperative patientsPre-intervention

Rate of study recruitment

Secondary Outcome Measures
NameTimeMethod
Aim 1: Preoperative training protocolUp to two weeks pre-operatively

Duration of preoperative training session

Aim 2: Effect of technology on pain30 minutes after using technology

Pains scores will be collected. Pain will be rated using the numerical rating scale. Participant will rate their pain from 0 - 10. 0 meaning no pain and 10 being the worst pain imaginable.

Aim 2: Rate of study retentionDuration of study up to 30 days

Assessment of ability to retain patients in pilot clinical trial

Aim 2: Effect of technology on anxietyImmediately after using technology

Anxiety scores will be collected. Anxiety will be rated from 0 - 10. 0 meaning no anxiety 10 being severe anxiety.

Aim 2: Treatment-specific satisfactionPost intervention up to two weeks

Qualitative feedback from participants using semi-structured interview to assess intervention satisfaction

Aim 1: Post-operative session protocolUp to two weeks post surgery

Duration of post-operative intervention session

Aim 2: Rate of study enrollment/randomizationPre-intervention

Assessment of ability to enroll and randomize patients in pilot clinical trial

Aim 2: Rate of treatment adherenceDuration of study up to 30 days

Assessment of patient adherence to study protocol

Aim 2: Effect of technology on medication useDuration of hospital stay (2-7 days)

Medications used will be collected

Aim 2: Self-Reported OutcomesDay of hospital discharge (Postoperatively 2-7 days)

Semi-structured interview

Trial Locations

Locations (1)

Nemours Children's Hospital

🇺🇸

Wilmington, Delaware, United States

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